Abstract:BACKGROUND AND PURPOSE:Osteoma cutis of the face represents a primary or secondary formation of ossific foci in the facial skin. Its primary form has been sparsely described in the plastic surgery and dermatology literature. As radiologists, we routinely encounter incidental, very small facial calcified nodules on CT studies performed for a variety of unrelated reasons. We hypothesized that this routinely encountered facial calcification represents primary miliary osteoma cutis and is a common, benign, age-rel… Show more
“…So far, 70 cases of MMOC have been reported. In a recent radiological study, Kim et al (6) described facial calcified nodules compatible with miliary osteomas as a very common finding in routine CT images of the head, suggesting that MMOC is probably underdiagnosed. In 1928 Hopkins first suggested the association with acne and afterwards a previous history of acne has been described in 55% of cases of MMOC (5).…”
“…So far, 70 cases of MMOC have been reported. In a recent radiological study, Kim et al (6) described facial calcified nodules compatible with miliary osteomas as a very common finding in routine CT images of the head, suggesting that MMOC is probably underdiagnosed. In 1928 Hopkins first suggested the association with acne and afterwards a previous history of acne has been described in 55% of cases of MMOC (5).…”
“…Authors regard MMOC as uncommon [22], rare [3,7,10,12,13], or very rare [14], while a few consider it as a relatively common, but under-recognized, condition [5,15,75]. Previous and recent imaging studies support this latter view.…”
Section: Epidemiologymentioning
confidence: 99%
“…Kishi et al [76] performed a dental radiographic study and found skin osteomas in 2.2% (48 of 2,089) subjects, while Shigehara et al [77] reported an incidence of 27.8% (44 of 158) based on a similar X-ray investigation. More recently, Kim et al [75] conducted a retrospective analysis of 1,315 sinus computerized tomography (CT) scans and identified a 42.1% prevalence of facial calcified nodules. It is interesting that these lesions were mostly found on the frontal and maxillary regions, overlapping the preferential distribution of osteomas identified in this review.…”
Multiple miliary osteoma cutis consists of heterotopic foci of bone tissue in the dermis and subcutaneous tissue. Patients usually present with multiple, asymptomatic facial papules of several millimetres in diameter which cause distress regarding their cosmetic appearance. The condition is described as rare, as only a few cases have been reported since its first description in 1864 by Virchow. We therefore carried out a comprehensive literature search and review, in which 102 published cases were retrieved and analysed. The demographic and clinical aspects, as well as current therapy solutions, of this probably overlooked condition are discussed.
“…Past and recent imaging studies found incidental skin osteomas and calcified nodules of the face ranging from 27.8% to 42.1% in routine X-ray and computed tomography (CT) scan analysis, respectively. 5,6 MMOC is then seemingly under-diagnosed with mostly subclinical lesions passing under the radar during clinical examination leading to only obvious cases of aesthetically conscious patients consulting for such condition. Misdiagnosis and the benign behaviour of the condition may also contribute to under-reporting.…”
Facial multiple miliary osteoma cutis is a variant of osteoma cutis usually occurring in women with a previous history of acne vulgaris. Successful ablative laser treatment has been reported using both CO2 and Er:YAG lasers among other invasive treatment modalities, like surgical removal. We report a patient with biopsy-proven facial multiple miliary osteoma cutis responding to non-ablative Q-switched Nd:YAG laser therapy. The patient had excellent cosmesis without textural changes or hypopigmentation despite her Asian background after three sessions over 6 months. Multiple miliary osteoma cutis is therefore now amenable to non-surgical non-ablative therapy by using Q-switched Nd:YAG laser therapy reducing the risk of textural changes and hypopigmentation, especially in dark complexion and high-risk individuals. To our knowledge, this treatment approach has not been previously reported.
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