2005
DOI: 10.1111/j.1525-1438.2005.00198.x
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Benign multicystic peritoneal mesothelioma: cases reports in the family with diverticulosis and literature review

Abstract: We report on benign multicystic peritoneal mesothelioma in two siblings whose family had a history of multiple familial diseases including diverticulosis. After a genetic evaluation and a chromosomal analysis, we were not able to identify a specific genetic cause of the family's pattern of disease. We assumed that previous surgical procedures and the chronic inflammatory process from diverticulitis were the underlying etiology. Both patients had multiple recurrences with indolent courses similar to those repor… Show more

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Cited by 38 publications
(44 citation statements)
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“…El MMPB es una lesión infrecuente, caracterizado por quistes multiloculados, múltiples o solitarios, de paredes delgadas de contenido seroso o hemático 7 . Aunque su patogénesis aún se desconoce, se han propuesto cinco hipótesis con respecto a su origen: inflamatorio, neoplásico, genético, hormonal y embriológico 5 .…”
Section: Discussionunclassified
See 1 more Smart Citation
“…El MMPB es una lesión infrecuente, caracterizado por quistes multiloculados, múltiples o solitarios, de paredes delgadas de contenido seroso o hemático 7 . Aunque su patogénesis aún se desconoce, se han propuesto cinco hipótesis con respecto a su origen: inflamatorio, neoplásico, genético, hormonal y embriológico 5 .…”
Section: Discussionunclassified
“…En relación a lesiones benignas, los diagnósticos diferenciales más importantes incluyen el linfangioma quístico o tumor adenomatoide, mientras que el diagnóstico diferencial con respecto a lesiones malignas incluye al mesotelioma maligno y tumores serosos que invaden el peritoneo 1,4 . Finalmente, el diagnóstico definitivo sólo se puede determinar a través de la histopatología 3,9 , donde puede observarse metaplasia adenomatoidea focal o escamosa 7 . El uso de tinciones de inmunohistoquímica específicas para células mesoteliales, como la calretinina y citoqueratina 5/6, permite la distinción entre MMPB y otras entidades 3,5 .…”
Section: Discussionunclassified
“…Focal adenomatoid or squamous metaplasia may be seen. 5 Mitosis and atypical cells are usually rare. Mesothelial cells stain positive for calretinin, thrombomodulin, and cytokeratin 5/6, and these markers allow for a differential diagnosis between BMPM and serum papillar carcinoma of the peritoneum.…”
Section: Introductionmentioning
confidence: 98%
“…[1][2][3] Most important causative factor being pelvic inflammatory disease. 4 Other causes being prior abdominal surgery. 4 It can be mistaken for a malignant lesion at surgery.…”
Section: Introductionmentioning
confidence: 99%
“…4 Other causes being prior abdominal surgery. 4 It can be mistaken for a malignant lesion at surgery.…”
Section: Introductionmentioning
confidence: 99%