Benign pancreatic vipoma

Canosa, Marlén Alvite; Fernández, Lucía Silva; López, Marta Seoane; Grobas, J. Pérez; Díaz, M. Berdeal; Freire, M.; Alejandro, Alberto Bouzón; Dovigo, Alba Gómez; González, Javier Aguirrezabalaga

doi:10.4321/s1130-01082011000400014

Cited by 2 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of these, 15 patients (15/30, 50%) were male and 15 patients (15/30, 50%) were female [Figure 2]. [23456789101112131415161718192021222324252627282930]…”

Section: Resultsmentioning

confidence: 99%

Prevalence of diagnostic methods and treatment modalities in vipoma patients: A rare cause of hormone-mediated diarrhea

Amiri

2019

Indian J Endocr Metab

View full text Add to dashboard Cite

Introduction: VIPoma is a neuroendocrine tumor that secrets vasoactive intestinal peptide and produces a well-defined clinical syndrome characterized by watery diarrhea, hypokalemia, hypochlorhydria and metabolic acidosis. The aim of this study to investigate clinical studies about diagnostic and therapeutic modalities of vipoma patients. In this retrospective study, all patients of vipoma were investigated. Clinical features, laboratory data at initial presentation, management and outcomes were collected. Subjects and Methods: The paper has written based on searching PubMed and Google Scholar to identify potentially relevant articles or abstracts. Categorical variables as percentage and continuous variables were reported as mean ± standard deviation (SD). Results: All the patients presented with watery diarrhea (30/30, 100%) and dehydration was reported in 33.3% of them. Prevalence of laboratory findings in these patients were assessed for hypokalaemia (25/30, 83.3%), metabolic acidosis (9/30, 33.6%), hypochloremia and achlorhydria (2/30, 6.6%). Elevated VIP levels have been seen in 73.3% patients with mean values of 882.85 ± 1134.87 pg/ml. Prevalence of diagnostic methods included CT scan in 19 patients (19/30, 63.3%), ultrasonography (15/50, 50%), and somatostatin receptor scintigraphy (8/30, 26.6%). Medical treatments included somatostatin and analogues in 18 patients (18/30, 60%). Surgery included less percentage of treatment in these patients. Conclusion: CT scan can be used as a reliable modality for diagnosis of vipoma and somatostatin analogues can be used as the most effective treatment in vipoma patients. Surveillance of these patients needs to close monitoring of patients via history, physical examination, laboratory and imaging.

show abstract

“…Of these, 15 patients (15/30, 50%) were male and 15 patients (15/30, 50%) were female [Figure 2]. [23456789101112131415161718192021222324252627282930]…”

Section: Resultsmentioning

confidence: 99%

Prevalence of diagnostic methods and treatment modalities in vipoma patients: A rare cause of hormone-mediated diarrhea

Amiri

2019

Indian J Endocr Metab

View full text Add to dashboard Cite

show abstract

“…Elevated pancreatic polypeptide levels confirm the diagnosis. 62 VIPomas, which arise from the pancreas in 90% 63 of adult cases, autonomously secrete VIP, 64 leading to a syndrome initially described by Verner and Morrison in 1958 of watery diarrhea, hypokalemia, and achlorhydria. 65 Like gastrinomas, insulinomas, glucagonomas, and somatostatinomas, VIPomas are associated with MEN-1 syndrome.…”

Section: Types and Clinical Featuresmentioning

confidence: 99%

Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas

Oronsky¹,

et al. 2017

View full text Add to dashboard Cite

This review covers the diverse topic of neuroendocrine neoplasms (NENs), a relatively rare and heterogeneous tumor type, comprising ~2% of all malignancies, with a prevalence of <200,000 in the United States, which makes it an orphan disease (Basu et al., 2010).1 For functional purposes, NENs are divided into two groups on the basis of clinical behavior, histology, and proliferation rate: well differentiated (low grade to intermediate grade) neuroendocrine tumors and poorly differentiated (high grade) neuroendocrine carcinoma (Bosman et al., 2010)2; this histological categorization/dichotomization is highly clinically relevant with respect to impact on treatment and prognosis even though it is not absolute since a subset of tumors with a low-grade appearance behaves similarly to high-grade lesions. Given the relative dearth of evidenced-based literature about this orphan disease as a whole (Modlin et al., 2008),3 since the focus of most articles is on particular anatomic subtypes of NENs (i.e., gastroenteropancreatic or pulmonary), the purpose of this review is to summarize the presentation, pathophysiology, staging, current standard of care treatments, and active areas of current research.

show abstract

Benign pancreatic vipoma

Cited by 2 publications

References 4 publications

Prevalence of diagnostic methods and treatment modalities in vipoma patients: A rare cause of hormone-mediated diarrhea

Prevalence of diagnostic methods and treatment modalities in vipoma patients: A rare cause of hormone-mediated diarrhea

Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas

Contact Info

Product

Resources

About