Benign Superior Vena Cava Syndrome

Mahajan, Vijay; Strimlan, Vaughn; Ordstrand, Howard S. Van; Loop, Floyd D.

doi:10.1378/chest.68.1.32

Cited by 112 publications

(34 citation statements)

References 38 publications

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“…This could be attributed to the higher relative frequency of lymphomas among Saudi patients, as has been shown in many published epidemiological studies [14][15][16] about cancer in Saudi Arabia. All benign underlying disorders of SVCO in our report have been reported in previous reports [11,17].…”

Section: Discussionsupporting

confidence: 78%

“…Accurate histological diagnosis may be difficult after the initiation of radiotherapy treatment. Furthermore, SVCO is rarely an emergency because patients with SVCO secondary to non-malignant causes have survived as long as 28 years [17]. The ominous nature of SVCO in patients with oncological emergencies is not related to the obstruction in itself, but rather to the underlying malignancy.…”

Section: Discussionmentioning

confidence: 99%

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Superior Vena Caval Obstruction: King Khalid University Hospital Experience

Ajarim

1992

Ann Saudi Med

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A five year experience, in 21 patients with superior vena caval obstruction (SVCO) was reviewed. SVCO was due to benign conditions in four patients (19%) and malignant tumors in 17 patients (81%). Lymphoma and lung cancer were the most common causes encountered. The most common symptoms and signs were facial swelling, shortness of breath, jugular venous distention, swelling of face and arms, and engorgement of thoracic veins. Benign disorders had a longer duration of symptoms before presentation and required longer time to make the diagnosis than in malignant disorders. No serious complications resulted from the superior vena cava obstruction itself or the investigative procedures leading to the diagnosis. Prognosis and response to treatment were dependent on the underlying cause of SVCO. Chemotherapy was effective in induction of complete regression of SVCO in the majority of patients with underlying malignant disorders. We conclude that SVCO should be approached invasively for diagnosis and tissue diagnosis of the underlying disorder should dictate the appropriate therapy.

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Section: Discussionsupporting

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Superior Vena Caval Obstruction: King Khalid University Hospital Experience

Ajarim

1992

Ann Saudi Med

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“…22,23 Though longterm data is not available, stent angioplasty for SVC Vascular Medicine 1999; 4: 33-36 obstruction appears to be a safe and effective method of treatment. [3][4][5][6][7][11][12][13][14][15][16][17]20,21 …”

Section: Discussionmentioning

confidence: 99%

Relief of sleep apnea after intravascular stenting for superior vena cava syndrome

et al. 1999

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“…However, the obstruction can result from a benign process in a small number of patients. Among benign aetiologies are tuberculosis, retrosternal thyroid, aortic aneurysm and thymoma [2]. We present the case of a patient with Klebsiella pneumoniae pneumonia of the right upper lobe, complicated by superior vena cava syndrome.…”

mentioning

confidence: 99%

A case of superior vena cava syndrome caused by Klebsiella pneumoniae

Kim¹,

Lim²,

Koh³

et al. 1997

Eur Respir J

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A 27 yr old man presented with productive cough, fever and manifestations of superior vena cava syndrome. He was an alcoholic but had been in good health until 3 days prior to admission. The physical examination, the chest radiograph and the results of the sputum culture were compatible with Klebsiella pneumoniae pneumonia of the right upper lobe. The superior vena cava scintigram using technetium-99m showed near total occlusion of the superior vena cava, while sputum cytology, chest computed tomography, and bronchoscopy were all negative for malignant aetiology.Antibiotic therapy brought about slow resolution of the pneumonia and also of the superior vena caval obstruction. The follow-up scintigram showed normalized venous flow of the superior vena cava. To our knowledge, this is the first case of superior vena cava syndrome developed in probable association with Klebsiella pneumoniae pneumonia.

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Benign Superior Vena Cava Syndrome

Cited by 112 publications

References 38 publications

Superior Vena Caval Obstruction: King Khalid University Hospital Experience

Superior Vena Caval Obstruction: King Khalid University Hospital Experience

Relief of sleep apnea after intravascular stenting for superior vena cava syndrome

A case of superior vena cava syndrome caused by Klebsiella pneumoniae

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