Benign Tumors and Tumor-like Lesions of the Vulva

Heller, Debra S.

doi:10.1097/grf.0000000000000133

Cited by 41 publications

(42 citation statements)

References 17 publications

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“…The differential diagnosis of a solid growth the Bartholin's gland include leiomyoma, primary carcinoma, and leiomyosarcoma and other vulvar mesenchymal lesions such as cellular angio broma, angiomyo broblastoma and aggressive angiomyxoma. (22)(23)(24). Leiomyosarcomas of the vulva are very rare, thus frequently mistaken for benign Bartholin's gland lesions, which delays the diagnosis and management.…”

Section: Discussionmentioning

confidence: 99%

“…The Bartholin's cyst is less painful but may cause local discomfort and often associates with history of recurrent Bartholin's abscesses. A recent systematic review found that there is no current randomised trial evidence to support the use of any single surgical intervention for the treatment of a symptomatic cyst or abscess of the Bartholin's gland (22)(23)(24)(25)(26).…”

Section: Discussionmentioning

confidence: 99%

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Challenges in Management of Bartholin gland Leiomyoma: A Case Report

Vinturache

Ismail

Damato

et al. 2020

Preprint

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Abstract Background: Leiomyomas are uncommon vulvar neoplasms often misdiagnosed as other Bartholin gland pathology. Due to their rarity and the absence of guidelines, their diagnosis and management remain challenging, largely based on expert opinion and evidence from case reports. Case Presentation: This case report describes a 44-year-old woman presenting with accelerating growth of a vulvar mass. Based on clinical signs and symptoms, the initial diagnosis was Bartholin cyst. Surgical excision was provided for symptom control and aesthetic reasons. The histopathologic diagnosis was vulvar leiomyoma. The postoperative recovery was complicated by secondary haematoma and dehiscence of the surgical site. There was no recurrence at two years follow up. Therefore, we discuss the dilemma posed by physical examination of a vulvar mass, the challenges of the management, and report on secondary morbidity and long-term follow up, aspects of care for patients with vulvar pathology not commonly addressed in the literature. Conclusions: Bartholin gland neoplasms are rare tumors, commonly misdiagnosed as Bartholin’s cysts. Excision is the treatment of choice. Short time follow up allows prompt management of potential postoperative complications. Continuing long term follow up is recommended due to recurrence risk.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Challenges in Management of Bartholin gland Leiomyoma: A Case Report

Vinturache

Ismail

Damato

et al. 2020

Preprint

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“…Granular cell tumours usually present as solitary, pale lesions that are slow growing and are relatively painless. The differential diagnosis would be Bartholin's gland tumour, sebaceous cyst, lipoma and papilloma [3]. Histologically, granular cell tumours are found in the dermis and the main morphological feature is the granularity of the cytoplasm, which is caused by massive accumulation of phagolysosomes.…”

Section: Discussionmentioning

confidence: 99%

Atypical Granular Cell Tumour of the Vulva

Meadley¹

2017

BJSTR

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“…Histologically, the skin appears thin with loss of the crevices found between the nipples. Surface skin is vitrified, and a set of chronic inflammatory cells is observed beneath it [48][49][50][51][52][53].…”

Section: Squamous Cell Hyperplasiamentioning

confidence: 99%

Depigmentation’s Disorders of the Vulva, Clinical Management

Tsikouras¹,

Anthoulaki²,

Deftereou³

et al. 2019

Depigmentation

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The cancer of the vulva is a rare disease with a positive association to poor developing countries. However, the incidence of vulvar cancer in situ nearly doubled in the last two decades and remained relatively stable. The main reason for this increased incidence of vulvar intraepithelial neoplasia (VIN) in women younger than 45 years is due to changes in sexual behavior, first intercourse at early age, multiple sexual partners, and sexually transmitted diseases that were increasing progressively. Furthermore, it is strongly associated with smoking and the increased incidence of HPV infection. The occurrence of early symptoms of VINlike pruritus vulvae, pain, and lichen sclerosus led to early diagnosis to perform the adequate treatment. VIN tends to appear multifocal, while most invasive cancers are unilateral located and appeared with well-circumscribed lesions.

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Benign Tumors and Tumor-like Lesions of the Vulva

Abstract: A variety of mass lesions may affect the vulva. These may be non-neoplastic, or represent benign or malignant neoplasms. A review of benign mass lesions and neoplasms of the vulva is presented.

Cited by 41 publications

References 17 publications

Challenges in Management of Bartholin gland Leiomyoma: A Case Report

Challenges in Management of Bartholin gland Leiomyoma: A Case Report

Atypical Granular Cell Tumour of the Vulva

Depigmentation’s Disorders of the Vulva, Clinical Management

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