Benign ulcers of the colon

Shah, Nayan C.; Ostrov, Arthur; Cavallero, Joseph B.; Rodgers, Joseph T.

doi:10.1016/s0016-5107(86)71767-7

Cited by 7 publications

(3 citation statements)

References 7 publications

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“…Data on cohorts of patients with non-specific ulcers or erosions of the colon are aged and scarce. [36][37][38] Eosinophilic colitis, related to allergies, similarly, are more frequent in a pediatric setting. Moreover, an association between positivity to allergic tests and symptoms is not well established in adults.…”

Section: Other Causes Of Nicmentioning

confidence: 99%

Endoscopic features of non-IBD colitis

Pigò,

Reggiani Bonetti Luca,

Conigliaro Rita

2023

Asian J Med Sci

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Background: Studies about the endoscopic aspect of non-inflammatory bowel disease (IBD) colitis are scarce. Aims and Objectives: The aim of this retrospective study was to describe the endoscopic appearance of non-IBD colitis (NIC) in an outpatient cohort. Materials and Methods: All cases of NIC, from 2018 to 2021, with a recent outpatient colonoscopy, were enrolled. Diagnosis was based on clinical, endoscopic, and histological characteristics, and follow-up ≥6 months to recognize misdiagnosed IBD because of mimic causes. Results: 158 patients (63 males, age 54 years±19) performed a colonoscopy with a final diagnosis of NIC associated with drug-exposition (74), food allergies (26), recent/active gastrointestinal infections (20), ischemic colitis (14), segmental colitis associated diverticulosis (SCAD) (10), obstructed defecation syndrome (ODS) (8) and microscopic colitis (6). Frequencies of endoscopic features and colon distribution were: Drug exposition (hyperemia, erosions/ulcers, 88%; right colon, 70%), recent infection (erosions, 60%; left colon/rectum, 88%), food allergies (red spots/erosions, 67%; all the colon), ischemic colitis (ulcers, 86%; right or left colon), SCAD (hyperemia/edema, 75%; always left colon), ODS (hyperemia, erosions, and loss of vascularity, 90%; always rectum), microscopic colitis (edema and hyperemia; all the colon). Conclusion: Drug-exposition is the most frequent cause of out-patient NIC. In an appropriate diagnostic context, red spots, hyperemia, and erosions are associated with drug expositions, recent infections, and food allergies. Ulcers are more frequent with ischemic colitis or drug-exposition.

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Section: Other Causes Of Nicmentioning

confidence: 99%

Endoscopic features of non-IBD colitis

Pigò,

Reggiani Bonetti Luca,

Conigliaro Rita

2023

Asian J Med Sci

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“…Colonoscopy permits direct visualization of the lesion, biopsy, and evaluation of the rest of colon. Multiple biopsies of the NSCUs are required to rule out malignancy, tuberculosis, parasitic infection, or other rarer causes of colonic ulceration [12]. If biopsy specimens reveal only benign inflammatory changes, conservative supportive management is recommended, with the expectation of spontaneous improvement within 2 ± 3 weeks.…”

Section: Diagnosismentioning

confidence: 99%

“…The condition's documented characteristics appear essentially unchanged over the years: a nearly equal sex ratio, age distribution between childhood and 80 years, peak incidence in the fifth decade of life, nearly half of the ulcers located in the cecum and 10 ± 15 % in the ascending colon [1 ± 15]. Various terms have been proposed for these ulcers, based on their size and location throughout the colon-including nonspecific ulcers [4], idiopathic ulcers [5,6], cecal ulcers [7,8], solitary ulcers [9,10], benign ulcers of the cecum [11] or colon [12], simple ulcers of the colon [13,14], and discrete colonic ulcers [15].…”

Section: Introductionmentioning

confidence: 99%

Nonspecific Ulcers of the Colon

Losanoff

Richman²,

Foerst³

et al. 2003

Endoscopy

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Nonspecific colonic ulcers (NSCUs) are rare and potentially life-threatening lesions of unknown etiology; the diagnosis is based on histologic findings showing nonspecific inflammatory changes. The condition's variable symptoms can include nonspecific abdominal discomfort, gastrointestinal bleeding, perforation, and peritonitis. Radiologic imaging can be helpful in locating the lesions, but colonoscopy facilitates early definitive diagnosis and aggressive treatment. The potential of NSCUs to recur is currently unknown, and morbidity rates remain high. Long-term colonoscopic follow-up may improve the prognosis.

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“Nonspecific” erosions and ulcers of the colonic mucosa

Rubio

Nydahl

1994

Digest Dis Sci

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A total of 26 cases of "nonspecific" erosions and ulcers of the colonic mucosa are reported. The most common causes were previous abdominal irradiation or ischemic disease due to arteriosclerosis. The lesions were localized to all segments of the colon. Of the 26 cases, five (19.2%) had erosions (ie, not penetrating beyond the muscularis mucosae) and the remaining 21, ulcers (ie, penetrating beyond the muscularis mucosae). In seven of the 26 cases (26.9%) more than one ulcer was found in the same specimen. Erosions may heal completely by epithelial regeneration (ie, restitutio ad integrum) while ulcers usually heal by replacing scarring tissue. Thus, the two lesions may not be clinically synonymous. The relatively high proportion of erosions among nonspecific ulcerations of the colonic mucosa has not been previously pointed out in the literature.

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Benign ulcers of the colon

Cited by 7 publications

References 7 publications

Endoscopic features of non-IBD colitis

Endoscopic features of non-IBD colitis

Nonspecific Ulcers of the Colon

“Nonspecific” erosions and ulcers of the colonic mucosa

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