Benignes zellreiches fibröses Histiozytom der Großzehe mit knöchernen Defekten des Nagelkranzfortsatzes

Kurzen, Hjalmar; Hartschuh, Wolfgang

doi:10.1007/s00105-002-0452-7

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…[ 15 ] It shows diffuse positivity for CD34 rather than factor XIIIa. [ 16 ] In this study, results of immunohistochemistry showed the expression of factor XIIIa and α-smooth muscle actin in the CFH lesion. Factor XIIIa has been proposed to react with dendritic cells and is intensely expressed in cutaneous histiocytomas.…”

Section: Discussionmentioning

confidence: 57%

A clinicohistopathological analysis of cutaneous fibrous histiocytomas of the finger

2020

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Background: Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare. Objective: This study was undertaken to examine the clinicohistopathological features of CFH of the finger. Materials and Methods: This is a retrospective study of 12 CFHs located on fingers in a tertiary hospital in Korea. All case slides were retrieved from saved files. Results: Ages of the CHF of the finger affected individuals ranged from 9 to 48 years with a male-to-female ratio of 1.4:1. Picker's nodule or wart was the most common clinical diagnosis. In only 2 out of the 12 cases was the pre-biopsy diagnosis of CFH ventured. Fibrocollagenous type was the most common histological type. Majority of the cases were mitotically inactive, exhibiting only 0–1 mitoses per high-power field and there was no recurrence. Tumor cells were uniformly CD34 negative. Conclusion: Because CFH can resemble malignancies including dermatofibrosarcoma protuberans, a lack of familiarity with the occurrence of CFH of the finger may lead to more aggressive treatment. Dermatologists should include CFH in their differential diagnosis of circumscribed nodules on the fingers to ensure proper management.

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Section: Discussionmentioning

confidence: 57%

A clinicohistopathological analysis of cutaneous fibrous histiocytomas of the finger

2020

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Benign fibrous histiocytoma of bone in a paediatric population: a report of 6 cases

et al. 2011

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Case records and radiological investigations of six children with benign fibrous histiocytoma were studied retrospectively. BFH occurred in the femur (n = 2), tibia (n = 2) and fibula (n = 2). Clinically, patients reported pain from the lesion lasting several months (mean 6 months). The pain was not associated with pathological fracture in any patient. On X-rays, the lesions appeared as lytic and sharply demarcated with a sclerotic rim and fine trabeculations. The reported cases were located in the metaphysis and the diaphysis of the long bones. The tumour was restricted to bone, without periosteal or soft tissue reaction. Treatment consisted of careful intralesional curettage of the lesion; the defect was thereafter filled with bone bank graft or injectable phosphocalcic cement. The length of follow-up ranged from 24 months to 4.75 years (mean 35.2 months). One case presented with recurrence of the disease and required successful repeat intralesional curettage. Benign fibrous histiocytoma is probably underestimated among patients less than 20 years of age. This diagnosis should be considered in any child or teenager who presents with a non-ossifying fibroma accompanied by unexplainable pain or a rapid growing. Surgery restricted to the osteolytic lesion seems sufficient to achieve bone healing.

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Connective tissue tumors

Calonje¹,

Brenn²,

Lazar³

2012

McKee's Pathology of the Skin

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Benignes zellreiches fibröses Histiozytom der Großzehe mit knöchernen Defekten des Nagelkranzfortsatzes

Cited by 3 publications

References 15 publications

A clinicohistopathological analysis of cutaneous fibrous histiocytomas of the finger

A clinicohistopathological analysis of cutaneous fibrous histiocytomas of the finger

Benign fibrous histiocytoma of bone in a paediatric population: a report of 6 cases

Connective tissue tumors

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