While the idea of inspiration spans the history of the field, inspiration as a topic has been an under-studied phenomenon in the interpretation field. Thirty-three professional interpreters from 21 agencies across North America participated in dialog on the topic of inspiration in interpretation through Internet-based World Café sessions. The dialog was rich and thoughtful, and revealed that these interpreters believed that inspiration is the goal of interpretation and that the nine characteristics of inspiration identified in the literature and reviewed in our prior publication were relevant to interpretation: that inspiration is two-sided, transmissible, positive, individual, transcendent, unexpected, holistic, requires receptivity, and receptivity may be cultivated. Identified barriers to using an inspiration-based approach in interpretation included meeting the needs of agencies, and particularly the agency’s needs for quantitative measurements of attendance and impacts.