Benzodiazepine Fused Heterocycles Vi: A Convenient Synthesis of 2-Aryl-4-(4-Hydroxy-6-Methyl-2-Pyrone-3-Yl)-2,3-Dihydro-1,5- Benzothiazepines Using McM-41(h) Zeolite†

Abstract

Simple and convenient procedures have been developed for the synthesis of 2-aryl-4-(4-hydroxy-6-methyl-2-pyrone-3-yl)-2,3-dihydro-l,5-benzothiazepines (3a-e) by the condensation reaction between 2-aminothiophenol (1) and 3-cinnamoyl-4-hydroxy-6-methyl-2-pyrones(2a-e) with MCM-41(H) Zeolite in ethanol. Introduction :

Vibrational spectroscopic study of dehydroacetic acid and its cinnamoyl pyrone derivatives

“…Ramkumar et al used L1 and L5 to prepare the compounds that show a potential HIV-1 integrate inhibitory effect [28]. L1-L5 were also used for synthesis of 1,5-benzothiazepine derivatives [29][30][31][32].…”