Benzodiazepine Use in Older, Community-Dwelling Southern Californians: Prevalence and Clinical Correlates

Mayer-Oakes, S. Allison; Kelman, G.; Beers, Mark H.; Jong, Fred De; Matthias, Ruth E.; Atchison, Kathryn A.; Lubben, James E.; Schweitzer, Simone

doi:10.1177/106002809302700403

Cited by 41 publications

(22 citation statements)

References 38 publications

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“…Some studies have described a higher consumption of the medication among the oldest old 9,11 , but not all 8,10 . In general, worse health conditions are associated with the use of benzodiazepines, such as number of chronic diseases 12 , functional disability 13 , worse self-reported health 8,12 , coronary disease 8 , depressive symptoms 12,13,14 and insomnia 14 . Furthermore, benzodiazepine users consult physicians with greater frequency 13,15 and consume greater amounts of other medications 12,14 .…”

Section: Introductionmentioning

confidence: 99%

A population based study on health conditions associated with the use of benzodiazepines among older adults (The Bambuí Health and Aging Study)

et al. 2009

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The aim of this study was to assess the health conditions and use of health services among elderly users of benzodiazepines. The study was carried out in the city of Bambuí in Minas Gerais State, Brazil. Of 1,742 inhabitants aged over 60, 1,419 participated in the study. Information about benzodiazepine and the use of other medications was obtained by means of interviews and checking medication packaging. After adjustments for confounding variables, benzodiazepine remained significantly associated with poorer self reported health (prevalence ratio = 1.94 and 2.04 for reasonable and bad/very bad health, respectively), common mental disorders (1.33), myocardial infarction (1.42), number of doctor visits in the previous 12 months (1.90 and 2.24 for 2-3 and 4+ visits, respectively) and concomitant use of other medications (1.84 and 1.83 for 2-4 and 5+ medications). The results showed that the factors associated with the use of benzodiazepine were similar to those observed in the elderly in higher income countries. The concomitant use of benzodiazepines and two or more medications was highly prevalent (59.5%), characterizing a situation of risk, which deserves attention as a public health problem.

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Section: Introductionmentioning

confidence: 99%

A population based study on health conditions associated with the use of benzodiazepines among older adults (The Bambuí Health and Aging Study)

et al. 2009

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“…Benzodiazepines are known worldwide to be very useful psychotropic agents (1)(2)(3)(4) (6)(7)(8). Those reports suggest that the patient characteristics of female gender and elderly affect the regular use of benzodiazepines (6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

Regular Prescriptions for Benzodiazepines: A Cross-Sectional Study of Outpatients at a University Hospital

2006

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“…17,30 Some of the reported clinical correlates of benzodiazepine use in older subjects are the number of other medications taken, sleep disorders, and depression. 31 In addition, benzodiazepine users are more likely to be white and college educated. 31,32 Important limitations of the previous studies in this area include nonvalidated patient-reported health status measures and medication use, data from a limited geographic distribution, no data on benzodiazepine dosages used, no data on the proportion of benzodiazepine prescriptions that were ordered to be taken daily versus pro re nata (PRN), and no data on OTC sleep aid medication use or alcohol use.…”

mentioning

confidence: 99%

“…31 In addition, benzodiazepine users are more likely to be white and college educated. 31,32 Important limitations of the previous studies in this area include nonvalidated patient-reported health status measures and medication use, data from a limited geographic distribution, no data on benzodiazepine dosages used, no data on the proportion of benzodiazepine prescriptions that were ordered to be taken daily versus pro re nata (PRN), and no data on OTC sleep aid medication use or alcohol use. 31,32 The Cardiovascular Health Study provided the opportunity to examine patterns of drug use and their correlates in a large, multisite, population-based study of community-dwelling older adults.…”

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confidence: 99%

Correlates and prevalence of benzodiazepine use in community-dwelling elderly

Schulz²,

et al. 1998

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OBJECTIVE:To describe the prevalence of benzodiazepine use, sociodemographic and physical health factors associated with use, dosages taken, and directions for use among individuals aged 65 years and older. DESIGN:Cross-sectional analysis of baseline data from the community-based, prospective observational Cardiovascular Health Study. PATIENTS/PARTICIPANTS:Medicare eligibility lists from four U.S. communities were used to recruit a representative sample of 5,201 community-dwelling elderly, of which 5,181 participants met all study criteria. MEASUREMENTS AND MAIN RESULTS:Among participants, 511 (9.9%) were taking at least one benzodiazepine, primarily anxiolytics (73%). Benzodiazepines were often prescribed to be taken pro re nata (PRN "as needed"), and 36.5% of prescriptions with instructions to be taken regularly were taken at a dose lower than prescribed. Reported over-the-counter (OTC) sleep aid medication use was 39.2% in benzodiazepine users and 3.3% in nonusers. In a multivariate logistic model, the significant independent correlates of benzodiazepine use were being white (odds ratio [

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Benzodiazepine Use in Older, Community-Dwelling Southern Californians: Prevalence and Clinical Correlates

Abstract: Further clinical research should explore the relationship between BZD use among older patients and the BZD-associated adverse clinical factors we observed, as well as the association between multiple drug use and potential adverse outcomes in older BZD users.

Cited by 41 publications

References 38 publications

A population based study on health conditions associated with the use of benzodiazepines among older adults (The Bambuí Health and Aging Study)

A population based study on health conditions associated with the use of benzodiazepines among older adults (The Bambuí Health and Aging Study)

Regular Prescriptions for Benzodiazepines: A Cross-Sectional Study of Outpatients at a University Hospital

Correlates and prevalence of benzodiazepine use in community-dwelling elderly

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