Benzophenone Imine

Abstract

This feature focuses on a reagent chosen by a postgraduate, highlighting the uses and preparation of the reagent in current research

Stable synthetic equivalents of N-unsubstituted imines: Part 1. Synthesis

“…The vacuum pyrolysis of arylmethyl azides [158] seems to proceed through intermediate formation of nitrenes whose rearrangement via [1,2] hydride shift produces N unsubstituted imines that further undergo trimerization to give compounds (VIII) (Scheme 44). It was shown recently [162] that crystalline compounds (IX) [X = Cl 3 CCH(OH)] may be used as the stable and available synthetic analogs of N unsubstituted arylideneimines.…”

“…Imines can also behave as dienophiles in the Diels-Alder reaction to give pyridine derivatives and as dienes to yield quinoline derivatives through the Povarov reaction. However, the use of N unsubstituted imines in synthesis is con fined to a restricted number of mainly aromatic and alkylaromatic ketimines [1]. The instability of N unsubstituted imines often becomes a serious obstacle to the selection of synthesis strategy.…”