Benzophenone

Abstract

Benzophenone product: benzophenone

Organic Sunscreens. Research, Innovation and the Organic Synthesis Importance

“…5 A benzofenona (BZF) pode ser sintetizada via reações de alquilação de Friedel-Crafts entre benzeno e tetracloreto de carbono, na presença de AlCl 3 , com posterior hidratação. 61 Esta substância fornece boa fotoproteção UVB-UVA (284-340 nm), muito embora seu uso seja proibido em função de seu poder de irritação dérmica e ocular. Ainda assim, a BZF foi pioneira no alcance de muitos derivados (A-H) aprimorados (Figura 8).…”

Direct Syntheses of Diphenylmethanol Derivatives from Substituted Benzenes and CHCl3 through Friedel‐Crafts Alkylation and Post‐Synthetic Hydrolysis or Alcoholysis Catalyzed by Alumina

“…In practice, DPM is synthesized by the reduction of benzophenone or by a Grignard reaction between phenylmagnesium bromide and benzaldehyde [8] . The former benzophenone is produced by an AlCl 3 ‐mediated Friedel‐Crafts reaction of benzene and CCl 4 , and subsequent hydrolysis of the formed dichlorophenylmethane (Scheme 1, reaction (1)) [9] . In recent studies, DPM derivatives have also been synthesized using the corresponding benzophenone derivatives produced from substituted benzenes and oxalyl chloride, or from aryl Grignard reagents and 1,1′‐carbonyldiimidazole [Reactions (2) and (3), respectively] [10,11] .…”