�ber das Sanarelli-Shwartzman-Ph�nomen (sog. generalisierte Shwartzman-Ph�nomen) des Menschen

Böhle, A.; Krecke, H. J.

doi:10.1007/bf01490468

Cited by 53 publications

(2 citation statements)

References 62 publications

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“…Krecke (1959), Krecke (1964), Fox (1971), Harms et al (1971Harms et al ( /73), B6hm (1978 auf die Bedeutung des Schocks als pathogenetischen Faktor beim WFS hingewiesen. Krecke (1959), Krecke (1964), Fox (1971), Harms et al (1971Harms et al ( /73), B6hm (1978 auf die Bedeutung des Schocks als pathogenetischen Faktor beim WFS hingewiesen.…”

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Zur �tiologie und Pathogenese des Waterhouse-Friderichsen-Syndroms

Althoff

1982

Z Rechtsmed

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The Waterhouse-Friderischsen syndrome (WFS) is the morphological substrate of a rapidly, mostly irreversible shock due to endotoxemia similar to the Sanerelli-Shwartzman phenomenon. The following disturbances of microcirculation cause death. The findings of 13 postmortem examinations reveal that acute severe respiratory infections, especially of nose and throat as etiologic factors, are more frequent than meningitis. Apparently different pathogens and shock vary the couse of disease and symptomatology before death. Moreover, because of the rarity and intensity of the WFS, as yet unknown or unrecognized dispositional factors cannot be ruled out.

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Zur �tiologie und Pathogenese des Waterhouse-Friderichsen-Syndroms

Althoff

1982

Z Rechtsmed

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“…This serious complication, with a m ortality rate of over 50% endangers patients of every age group and in both sexes. Large num bers of cases have been reported in surgical, medical and uro logical literature [6,15,20,28,43,53,63], The most common portal of entry of infection in surgical cases is the genito-urinary tract and the intestinal tract following intestinal surgery, gall bladder opera tions and urological m anipulations. In pregnant women the most common source of septicemia is intrauterine infection, as a con sequence of abortion, or prem ature rupture of membranes.…”

Section: Introductionmentioning

confidence: 99%

Endotoxin Shock in Pregnancy

Florek¹

1964

Gynecol Obstet Invest

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Venous infarction of the adrenal glands

Fox

1976

The Journal of Pathology

114

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An investigation of 78 cases of adrenal haemorrhage and necrosis disclosed that 32 were examples of adrenal venous infarction. In all these cases there was thrombosis of the main adrenal vein and in most there was also thrombosis of the capsular veins, a finding which has not been well established. In a number of cases with venous infarction there was clinical and pathological evidence that disseminated intravascular coagulation (DIC) had occurred, but it appears that it was not the direct cause of venous thrombosis. The majority of cases of venous infarction occur in patients with severe infection, frequently of the respiratory tract. Venous infarction was found in five cases with hypothermia an association which had rarely been described, and in three of these there was evidence of DIC. This is apparently the first occasion on which DIC has been demonstrated in cases of hypothermia in man. The cause of venous thrombosis in the adrenal glands is obscure in most cases of venous infarction, although in three it was due to involvement by metastatic carcinoma. It is suggested that the factors responsible for the initiation of thrombosis in the adrenal veins are catecholamines, thrombin, fibrin and endotoxin. Localisation of the thrombi to the adrenal vein is due to the unique anatomical structure of the vein which, under certain circumstances, results in the local stasis of blood.

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�ber das Sanarelli-Shwartzman-Ph�nomen (sog. generalisierte Shwartzman-Ph�nomen) des Menschen

Cited by 53 publications

References 62 publications

Zur �tiologie und Pathogenese des Waterhouse-Friderichsen-Syndroms

Zur �tiologie und Pathogenese des Waterhouse-Friderichsen-Syndroms

Endotoxin Shock in Pregnancy

Venous infarction of the adrenal glands

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