�ber den einflu� der luftverschmutzung auf den paraffingehalt der hautoberfl�chenlipide

Gloor, M.; Josephs, H. W.; Friederich, H. C.

doi:10.1007/bf00561195

Cited by 11 publications

(3 citation statements)

References 15 publications

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“…In the cosmetics branch great efforts are made to avoid these undesirable effects. Mild surfactants attack the intercellular lipids to a considerably lesser extent than more aggressive surfactants with a similar cleansing performance [11,12]. The lipid film, or at least a part of it, can be restored by refatting oil additives or creams applied after washing [13, 19±21].…”

Section: Introductionmentioning

confidence: 99%

Infrared spectroscopy of the skin: influencing the stratum corneum with cosmetic products

Prasch

Knübel

Schmidt-Fonk

et al. 2000

Intern J of Cosmetic Sci

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The stratum corneum is the outermost layer of the skin and, as such, represents the decisive barrier between the body and the environment. The combination of horny cells and lamellar lipid layers prevents water loss from the body and protects it against penetration by exogenous substances. For selective investigation of the thin outermost stratum corneum layer ATR-FTIR (attenuated total reflection Fourier transform infrared) spectroscopy has proved itself in practice. It provides information about the sebum content, type of fatty substances, water content and degree of order of the lamellar lipid film in the stratum corneum. Different types of skin (dry, normal and greasy) differ mainly in their sebum content but also in the composition of their fats and the degree of order of their lipids. A comparison with model lipid mixtures shows that the stratum corneum lipids are mainly present in a fixed gel form under physiological conditions. In cleansing processes a large part of the sebum is removed from the skin. The skin reacts to the defatting process by the rapid secretion of sebum. After cleansing with a mild face cleansing emulsion the re-achievement of the same fat status takes longer than with a surfactant shower gel. Skin creams cause alterations to the skin moisture and in the degree of order of the stratum corneum lipids. A lamellar cream with a structure similar to that of the stratum corneum lipids increases the degree of order of the alkyl chains of the skin lipid film (biomimetic principle), whereas a conventional w/o cream reduces this degree of order. Skin moisture increases after the use of the creams.

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Section: Introductionmentioning

confidence: 99%

Infrared spectroscopy of the skin: influencing the stratum corneum with cosmetic products

Prasch

Knübel

Schmidt-Fonk

et al. 2000

Intern J of Cosmetic Sci

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“…It is not known whether they represent a contami nation by sebaceous lipids [77] or from the environment [139). A significant quantity of hydrocarbons has been noted in the mammalian stratum corneum.…”

Section: Squalenes and N-alkanesmentioning

confidence: 99%

Stratum corneum Lipid Function

1991

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The stratum corneum contains a complex mixture of polar and nonpolar lipids in its intercellular spaces. These lipids, present in form of multiple lamellae, have been investigated for their role in providing the epidermal barrier to transcutaneous water loss, the selective barrier from the inside to the outside of the organism and partly the process of physiological desquamation. The composition of these lipids varies from species to species, with the body region and the degree of keratinocyte differentiation. The most undifferentiated layers of the epidermis contain typical membrane lipids, phospholipids, while more differentiated layers contain ceramides, cholesterol and free fatty acids. Essential fatty acids are essential for the maintenance of the lamellar structures and epidermal barrier function. Epidermal linoleic and arachidonic acids derive from exogenous sources. Only recently attempts have been made to elucidate the timing and regulation of epidermal fatty acid metabolism. Keratinocytes do not express a low molecular weight fatty acid binding protein like other cells active in lipid metabolism, but may employ alternative ways in fatty acid uptake and metabolism.

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“…A comparison with data reported previously is therefore difficult. Data for the back of volunteers have been reported by G loor et al [13][14][15] for petroleum ether. These values compare approximately to the values reported here if the replacement time of 2 h is taken into account.…”

Section: Resultsmentioning

confidence: 99%

Influence of Lipophilic Substances on Fungal Infections of the Human Skin

Schmid¹,

Chelf²

1976

Dermatology

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A three-factor factorial experiment was performed to assess the efficiency of lipid extraction from the back of human volunteers. Chloroform-methanol (2:1 v/v) proved substantially superior to acetone or diethyl ether. The latter two solvents were also significantly more efficient than n-hexane. The implication of the findings is discussed with regard to the isolation and characterization of fungistatic and bacteriostatic agents on the surface of the skin.

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�ber den einflu� der luftverschmutzung auf den paraffingehalt der hautoberfl�chenlipide

Cited by 11 publications

References 15 publications

Infrared spectroscopy of the skin: influencing the stratum corneum with cosmetic products

Infrared spectroscopy of the skin: influencing the stratum corneum with cosmetic products

Stratum corneum Lipid Function

Influence of Lipophilic Substances on Fungal Infections of the Human Skin

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