�ber den Gehalt von Follikelhormon (Menformon) im Harn von Menschen

Borchardt, H.; Dingemanse, E.; Laqueur, E.

doi:10.1007/bf01494921

Cited by 10 publications

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“…Kemp and Pedersen-Bjergaard [1933] employed this method, and more recently Borchardt, Dingemanse, and Laqueur [1934] published an improved version of the method in which an adequate amount of acid was used ; the method was applied to the extrac¬ tion of androgens [Dingemanse, Borchardt, and Laqueur, 1937], and the superiority of their technique was supported by later studies [Dingemanse and Laqueur, 1938]. EXTRACTION OF STEROIDS FROM URINE 91 Dr. K. Pedersen-Bjergaard kindly informed us, during this work, of the details of his current method, in which carbon tetrachloride was used as the extracting solvent instead of benzene.…”

Section: Conditions Of Hydrolysis Of Urine By Acid Under Varying Condmentioning

confidence: 98%

Methods of Extracting Compounds Related to the Steroid Hormones From Human Urine

Callow¹,

Callow²,

Emmens³

et al. 1939

Journal of Endocrinology

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At the beginning of biochemical work on male hormones it was assumed that the androgenic material which could be extracted from normal male urine was`the male hormone', or 'the testicular hormone'. On this supposition, it was hoped that the biological assay of urine extracts would give an index of the activity of androgenic substances in the human body, possibly referable to the level of testicular secretion. It is for this reason that the separation of the maximal androgenic activity as measured by capon comb-growth has been taken as the criterion of a satisfactory extraction in the methods developed by systematic work in various laboratories. It has since been realized, however, that androgenic activity is not specific to one substance, and that at least two related compounds with androgenic activity are present in the mixture of neutral compounds which can be prepared from urine. Further, these two compounds, androsterone and ¿ratts-dehydroandrosterone (¿35-androsten-3(/3)-ol-17-one), which can be isolated from the urine of women as well as from the urine of men [Callow and Callow, 1938], have not been found in tissue, whilst the only androgen isolated as yet from testis tissue, testosterone, has not been found in urine.

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Section: Conditions Of Hydrolysis Of Urine By Acid Under Varying Condmentioning

confidence: 98%

Methods of Extracting Compounds Related to the Steroid Hormones From Human Urine

Callow¹,

Callow²,

Emmens³

et al. 1939

Journal of Endocrinology

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show abstract

“…of male hormone, and 80-110 i.u. oestrogenic hormone [see also Borchardt et al 1934;Callow, 1936, 1]. The figures quoted above perhaps convey a somewhat misleading impression of the relative amounts of male and oestrogenic hormones present in the urine, and it should be remembered that whereas 100 i.u.…”

Section: (Received 14mentioning

confidence: 99%

Isolation of Δ3:5-androstadiene-17-one from the urine of a man with a malignant tumour of the adrenal cortex

Burrows

Cook

Roe

et al. 1937

Biochemical Journal

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Ovarium, Hypophyse, Placenta und Schwangerschaft in ihrer innersekretorischen Beziehung zur Frauenheilkunde

Clauberg¹

1936

Die Bedeutung Der Inneren Sekretion Für Die Frauenheilkunde

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�ber den Gehalt von Follikelhormon (Menformon) im Harn von Menschen

Cited by 10 publications

References 0 publications

Methods of Extracting Compounds Related to the Steroid Hormones From Human Urine

Methods of Extracting Compounds Related to the Steroid Hormones From Human Urine

Isolation of Δ3:5-androstadiene-17-one from the urine of a man with a malignant tumour of the adrenal cortex

Ovarium, Hypophyse, Placenta und Schwangerschaft in ihrer innersekretorischen Beziehung zur Frauenheilkunde

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