�ber die Rolle der Desoxyribosenukleins�ure bei der Zellteilung

The Nature of Differential Reactivity in the Heterochromatin of <i>Trillium</i> and <i>Paris</i> spp

“…Some time during interphase, the DNA content is doubled, by the synthesis of new DNA. Opinions still differ on the time of synthesis, thus Caspersson (1939) believed that synthesis took place during prophase. Pasteels and Lison (1950) concluded that synthesis took place at anaphase and telophase, whilst Walker and Yates (1952) and others decided that the increase in DNA took place in the latter half of interphase.…”

“…Following the work of Caspersson (1939) it was believed that DNA was deposited round the chromosomes at prophase, forming the chromosome "matrix" , and causing them to spiralise. Spiralisation could usually be correlated with the disappearance of the nucleolus, the RNA of which was assumed to be deposited (probably after conversion to DNA) as chromosome matrix.…”

Über Die «hellen Zellen» Im Epithel Der Menschlichen Uterusschleimhaut

“…Es ist bekannt, daß während der frühen Prophase bei noch in tak ter K ernm em bran der Gehalt des Zellkerns an Desoxyribo-nukleinsäure zunim m t (Flemming [1882], Heidenhain [1907], Was sermann [1926,1929], M jassojedoff [1927[ ], Caspersson [1939). Nach Ludwig [1954] wird dem Kern vom Nucleolus Ribosenuklein säure zur Synthese der Desoxyribonukleinsäure zur Verfügung ge stellt; dabei wird der Nucleolus leer und löst sich schließlich auf.…”

The Chemical Formulation of Gene Structure and Gene Action

“…Synthesis of both these ingredients is involved, but the two syntheses need not be simultaneous. Chromosomes entering a reproductive cycle first show a heavy increase of nucleic acid, and only afterward is there the beginning evidence of the chain of genes becoming reduplicated (33,46,65,117,133,(167)(168)(169).…”