Berylliosis: Summary and Survey of all Clinical Types in Ten Year Period

DeNardi, J.M.; Ordstrand, Howard S. Van; Curtis, Geo. H.

doi:10.3949/ccjm.19.4.171

Cited by 17 publications

(16 citation statements)

References 2 publications

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“…It is of interest that 10 cases were "neighbourhood" ones with t indirect exposure to beryllium, such as living down wind of a beryllium factory, washing beryllium workers' clothes, and fishing in the vicinity of a beryllium factory. Examples of such cases are described by DeNardi, Van Ordstrand, and Curtis (1952). Included in this group was a child of 7.…”

Section: Methodsmentioning

confidence: 99%

A Histological Study of the Lungs in 52 Cases of Chronic Beryllium Disease

Wj¹

1958

Occupational and Environmental Medicine

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Section: Methodsmentioning

confidence: 99%

A Histological Study of the Lungs in 52 Cases of Chronic Beryllium Disease

Wj¹

1958

Occupational and Environmental Medicine

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“…İlk ça-lışmalarda idrar berilyum seviyelerinin bu maksatla kullanılabileceği belirtilmiş; fakat maruz kalma süre-si veya hastalığın ciddiyeti ile korelasyon gösterme-miştir. 11,27 Buna rağmen, biyokimyasal analiz metotlarındaki gelişmeler berilyumun biyolojik taraması-nın değerini arttıracaktır. İndüktif eşleşmiş plazma kütle spektrometri (ICP-MS) kullanılarak, havadaki berilyum ile idrar berilyum seviyelerinin metalurji işçilerinde korelasyon içinde olduğu gösterilmiştir.…”

Section: Tanıunclassified

An industrial risk: Beryllium

Çaylak

Aytekin²

2012

J Clin Exp Invest

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Beryllium is a vocational disease factor and beryllium exposure can potentially lead to Chronic Beryllium Disease (CBD) in 2-6 % of workers. While acute lymphocytic pneumonia occurred in individuals who were exposed to high doses of beryllium, low dose exposure to beryllium followed by a long subclinical period can cause CBD characterized with chronic granulomatosis. It has been observed that varying amounts of beryllium exposure are necessary to produce symptoms of CBD or beryllium sensitization (BeS). Genetic differences between patients may be the underlying cause of these dose-effects and further study of the differences in patients exposed to beryllium may lead to earlier diagnosis and the identification of biomarkers of CBD. In this review, it is summarized the general properties of beryllium exposure, the immunopathogenesis and genetic differences of beryllium-induced diseases, genotoxicity and the carcinogenic effects of beryllium.

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“…Potentially, biological monitoring of beryllium or beryllium derivatives in biological fluids could be used to assess total bodily exposure. Early attempts at biological monitoring for beryllium observed that beryllium levels in urine were indicative of exposure, but did not correlate to exposure history or severity of disease (Klemperer et al 1951;DeNardi et al 1953;Stoeckle et al 1969). However, recent advances in analytical chemistry methods have greatly improved the feasibility of biological monitoring for beryllium (Wegner et al 2000;Apostoli and Schaller 2001).…”

Section: Dermal Exposurementioning

confidence: 99%