Best practice in healthcare environment decontamination

Siani, Harsha; Maillard, Jean‐Yves

doi:10.1007/s10096-014-2205-9

Cited by 54 publications

(51 citation statements)

References 124 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cleaning/disinfection technique, product, frequency, number of trained staff performing this process are also keys for reducing microbial contamination of hand‐touch sites, and thus reducing HAIs (Dancer et al . ; Siani and Maillard ; Kenters et al . ).…”

Section: Resultsmentioning

confidence: 99%

Biofilm contamination of high‐touched surfaces in intensive care units: epidemiology and potential impacts

Costa

Johani

Melo

et al. 2019

Lett Appl Microbiol

108

View full text Add to dashboard Cite

Significance and Impact of the Study: Contamination of healthcare facilities surfaces has been shown to play a major role in transmission of pathogens. The findings of this study show that dry surface biofilms are widespread and can incorporate pathogens and multidrug-resistant organisms (MROs). Biofilms on highly touched surfaces pose a risk to patients, as dry surface biofilms persist for long period and microorganisms within biofilm have been shown to be transmitted. This study also provides a better understanding of microbial populations in hospital environments, reinforcing that pathogens and MROs are found incorporated into biofilm, which impacts the difficulty in cleaning/disinfection. AbstractThe aim of this study was to determine the epidemiology (location, microbial load, microbiome, presence/absence of biofilm and pathogens, including ESKAPE-Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter species, and antimicrobial susceptibility profiles) of the bacterial contamination on intensive care units (ICUs) surfaces. Fifty-seven high-touched surfaces were collected from adult, paediatric and neonatal ICUs from two large public Brazilian hospitals from central and north regions. Samples (c. 4 cm 2 ) were subjected to culture (qualitative), qPCR targeting 16s rRNA gene (microbial load-bacteria per cm 2 ), 16s rRNA amplicon sequencing (microbiome analysis) and scanning electron (SEM) or confocal laser scanning microscopy (CLSM) (biofilm presence). Multidrug resistant organisms (MROs) were detected using specific chromogenic agar. The average bacterial load was 1Á32 9 10 4 bacteria per cm 2 , container for newborn feeding bottles, stretcher mattress, humidicrib mattress filling and computer keyboards presented the higher bioburden. However, only 45Á6% (26/57) were culture-positive, including 4/26 with MROs. ESKAPE organisms were detected in 51Á8% of the samples subjected to next-generation sequencing. Viability staining and CLSM demonstrated live bacteria on 76Á7% of culture-negative samples. Biofilm was present on all surfaces subjected to microscopy (n = 56), demonstrating that current cleaning practices are suboptimal and reinforcing that MROs are incorporated into hospital surfaces biofilm.

show abstract

Section: Resultsmentioning

confidence: 99%

Biofilm contamination of high‐touched surfaces in intensive care units: epidemiology and potential impacts

Costa

Johani

Melo

et al. 2019

Lett Appl Microbiol

108

View full text Add to dashboard Cite

show abstract

“…[12][13][14][15][16][17][18] Several reviews have concluded that improved cleaning leads to reductions in HAI. 11,19 However, there is a paucity of high-quality studies demonstrating that improved cleaning and disinfection reduces HAIs. 20,21 Importantly, the studies that have assessed interventions to improve cleaning have reported that after the intervention, approximately 5%-30% of surfaces remain potentially contaminated.…”

Section: Rationale For Using a No Touch Methods For Terminal Room Disimentioning

confidence: 99%

“…4,5 Over the last decade, substantial scientific evidence has accumulated that contamination of environmental surfaces in hospital rooms plays an important role in the transmission of several key health care-associated pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), Clostridium difficile, Acinetobacter spp, and norovirus. [6][7][8][9][10][11] In general, all of these pathogens share the following characteristics: ability to survive for prolonged periods of times on environmental surfaces, ability to remain virulent after environmental exposure, frequent contamination of the hospital environment, ability to colonize patients, ability to transiently colonize the hands of HCP, and transmission via the contaminated hands of HCP. 8 Norovirus and C difficile also are noted for a small inoculating dose and relative resistance to antiseptics and disinfectants used on environmental surfaces.…”

mentioning

confidence: 99%

Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials

Weber

Rutala

Anderson

et al. 2016

American Journal of Infection Control

164

148

View full text Add to dashboard Cite

Over the last decade, substantial scientific evidence has accumulated that indicates contamination of environmental surfaces in hospital rooms plays an important role in the transmission of key health care-associated pathogens (eg, methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, Clostridium difficile, Acinetobacter spp). For example, a patient admitted to a room previously occupied by a patient colonized or infected with one of these pathogens has a higher risk for acquiring one of these pathogens than a patient admitted to a room whose previous occupant was not colonized or infected. This risk is not surprising because multiple studies have demonstrated that surfaces in hospital rooms are poorly cleaned during terminal cleaning. To reduce surface contamination after terminal cleaning, no touch methods of room disinfection have been developed. This article will review the no touch methods, ultraviolet light devices, and hydrogen peroxide systems, with a focus on clinical trials which have used patient colonization or infection as an outcome. Multiple studies have demonstrated that ultraviolet light devices and hydrogen peroxide systems have been shown to inactivate microbes experimentally plated on carrier materials and placed in hospital rooms and to decontaminate surfaces in hospital rooms naturally contaminated with multidrug-resistant pathogens. A growing number of clinical studies have demonstrated that ultraviolet devices and hydrogen peroxide systems when used for terminal disinfection can reduce colonization or health care-associated infections in patients admitted to these hospital rooms.

show abstract

“…[178][179][180][181][182] Meticulous cleaning of hospital surfaces is therefore vital to maintain standards and reduce the risk of HCAIs. 183 Several studies conclude that ultraviolet devices and hydrogen peroxide vapor technologies successfully eradicate potentially dangerous hospital microorganisms adhering to the surfaces in ward or patient rooms. [183][184][185][186] Furthermore, hydrogen peroxide vapor efficiently sterilizes and sanitizes all clinical areas where potentially dangerous microbial MDR microorganisms and spores were suspected to be present.…”

Section: Hcaismentioning

confidence: 99%

Health care-associated infections – an overview

Haque¹,

Sartelli²,

McKimm³

et al. 2018

IDR

970

610

View full text Add to dashboard Cite

Health care-associated infections (HCAIs) are infections that occur while receiving health care, developed in a hospital or other health care facility that first appear 48 hours or more after hospital admission, or within 30 days after having received health care. Multiple studies indicate that the common types of adverse events affecting hospitalized patients are adverse drug events, HCAIs, and surgical complications. The US Center for Disease Control and Prevention identifies that nearly 1.7 million hospitalized patients annually acquire HCAIs while being treated for other health issues and that more than 98,000 patients (one in 17) die due to these. Several studies suggest that simple infection-control procedures such as cleaning hands with an alcohol-based hand rub can help prevent HCAIs and save lives, reduce morbidity, and minimize health care costs. Routine educational interventions for health care professionals can help change their hand-washing practices to prevent the spread of infection. In support of this, the WHO has produced guidelines to promote hand-washing practices among member countries.

show abstract

Best practice in healthcare environment decontamination

Cited by 54 publications

References 124 publications

Biofilm contamination of high‐touched surfaces in intensive care units: epidemiology and potential impacts

Biofilm contamination of high‐touched surfaces in intensive care units: epidemiology and potential impacts

Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials

Health care-associated infections – an overview

Contact Info

Product

Resources

About

Best practice in healthcare environment decontamination

Cited by 54 publications

References 124 publications

Biofilm contamination of high‐touched surfaces in intensive care units: epidemiology and potential impacts

Biofilm contamination of high‐touched surfaces in intensive care units: epidemiology and potential impacts

Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials

Health care-associated infections &ndash; an overview

Contact Info

Product

Resources

About

Health care-associated infections – an overview