Best practices during COVID-19 pandemic in solid organ transplant programs in Spain

Pascual, Julio; Mazuecos, Auxiliadora; Sánchez-Antolín, Gloria; Solé, Amparó; Ventura‐Aguiar, Pedro; Crespo, Marta; Farrero, Marta; Fernández-Rivera, Constantino; Garrido, Iris P.; Gea, Francisco; González-Monte, Esther; Rodríguez, Antonio Javier González; Hernández-Gallego, Román; Jiménez, Carlos; López-Jiménez, Verónica; Otero, Alejandra; Pascual, Sonia; Rodríguez-Laiz, G.; Ruiz, Juan Carlos; Sancho, Asunción; Santos, Francisco; Serrano, Trinidad; Tabernero, Guadalupe; Zárraga, Sofía; Delgado, Juan

doi:10.1016/j.trre.2023.100749

Transplantation Reviews

2023

DOI: 10.1016/j.trre.2023.100749

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Best practices during COVID-19 pandemic in solid organ transplant programs in Spain

Julio Pascual

Auxiliadora Mazuecos

Gloria Sánchez-Antolín

et al.

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“…The pandemic caused by the severe-acute-respiratory-syndrome coronavirus type 2 (SARS-CoV-2) has complicated the practice of solid organ transplantation (SOT) in several ways: i) reduction in the availability of donors [ 1 ]; ii) reduced response to SARS-CoV-2 vaccination; iii) risk of severe coronavirus infectious disease (COVID) from immunosuppression, both in vaccinated and unvaccinated subjects.…”

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confidence: 99%

Risk of severe COVID in solid organ transplant recipients

Barreiro,

Candel,

Carretero

et al. 2023

Rev Esp Quimioter

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Despite the fact that COVID is today not a life-threat for the general population, recipients of solid organ transplantation should be viewed as a high risk group for severe COVID. Repetitive doses of SARS-CoV-2 vaccine still fail to protect SOT recipients from infection, disease or even death caused by COVID. A more frequent need for medical care may initially place these patients at greater chances of SARS-CoV-2 infection. Immunosuppression after engrafting and underlying medical conditions that led to the practice of SOT contribute to more risk of severe infection. Immunosuppression also blunts the intensity of humoral and cellular responses after vaccination, even when several booster doses have been administered. Still, vaccination is the best strategy to prevent a fatal outcome in case of SARS-CoV-2 infection, with a particular reduction in mortality. SOT recipients should be considered a high-risk population that need yearly SARS-CoV-2 vaccination.

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mentioning

confidence: 99%

Risk of severe COVID in solid organ transplant recipients

Barreiro,

Candel,

Carretero

et al. 2023

Rev Esp Quimioter

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In-person versus virtual heart transplantation selection committee meetings: Longer-term impact on committee member perceptions and patient selection outcomes

Chen,

Shan,

Fraschilla

et al. 2024

JHLT Open

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Best practices during COVID-19 pandemic in solid organ transplant programs in Spain

Cited by 2 publications

References 44 publications

Risk of severe COVID in solid organ transplant recipients

Risk of severe COVID in solid organ transplant recipients

In-person versus virtual heart transplantation selection committee meetings: Longer-term impact on committee member perceptions and patient selection outcomes

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