1999
DOI: 10.1258/002367799780487913
|View full text |Cite
|
Sign up to set email alerts
|

Beta-adrenoceptor inhibition for induction of acute cardiac failure in pigs

Abstract: SummaryFor the testing of heart assist devices most animal models of acute cardiac failure that are usually used show certain disadvantages. We therefore developed a new method using the {3-adrenoceptor antagonist carazolol. We administered a bolus injection of 1 mg/kg followed by a continuous infusion of 1 mg/kg/h in adult German 'Landrasse' pigs. Blood pressure, heart rate, cardiac output and maximum left ventricular pressure rise time showed a significant (P < 0.05) reduction of the control value varying be… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2004
2004
2017
2017

Publication Types

Select...
3
1
1

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
references
References 12 publications
0
0
0
Order By: Relevance