Beta-blocker treatment of chronic systolic heart failure improves prognosis even in patients meeting one or more exclusion criteria of the MERIT-HF study

Jost, Andreas; Rauch, Bernhard; Hochadel, Matthias; Winkler, Ralph; Schneider, Steffen; Jacobs, Martina; Kilkowski, Caroline; Kilkowski, Andreas; Lorenz, Herbert; Muth, Kerstin; Zugck, Christian; Remppis, Andrew; Haass, Markus; Senges, Jochen

doi:10.1093/eurheartj/ehi473

Cited by 25 publications

(15 citation statements)

References 12 publications

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“…However, over the past two decades there has been a substantial reduction in mortality, probably due to more widespread use of renin-angiotensin aldosteron (RAAS) and beta-receptor blocking agents [2,4,5]. Studies from Sweden and from Scotland have shown that the prognosis has improved [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Are There Any Significant Differences Between Females and Males in the Management of Heart Failure? Gender Aspects of an Elderly Population With Symptoms Associated With Heart Failure

Alehagen

Ericsson

Dahlström

2009

Journal of Cardiac Failure

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An increasing interest has been shown in potential gender differences in treating patients with heart failure (HF), a serious condition for the individual. AimTo evaluate whether there are any differences in the prevalence of HF, cardiac function, biomarkers and the treatment of HF with respect to gender. MethodsAll persons age 70 to 80 in a rural municipality were invited to participate in the project; 876 persons accepted. Three cardiologists evaluated the patients including a new history, clinical examination, ECG, chest x-ray, blood samples, and Doppler echocardiography to assess both systolic and diastolic function. The patients were followed during a mean period of 8 years. Results and ConclusionFemales had hypertension more frequently and included fewer smokers than their male counterparts. A female preponderance was seen in those with preserved systolic function, whereas males predominated among those with systolic dysfunction. During the follow-up period, 20% of the males and 14% of the females died of cardiovascular diseases. The results did not show any inferior treatment of females with HF, but it clearly was more difficult to correctly classify female patients presenting with symptoms of HF.

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Section: Introductionmentioning

confidence: 99%

Are There Any Significant Differences Between Females and Males in the Management of Heart Failure? Gender Aspects of an Elderly Population With Symptoms Associated With Heart Failure

Alehagen

Ericsson

Dahlström

2009

Journal of Cardiac Failure

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“…Auch Patienten, die aufgrund von Ausschlusskriterien nicht in kontrollierte Studien eingeschlossen wurden, sollte eine leitlinienkonforme Therapie nicht grundsätzlich vorenthalten werden [19].…”

Section: Herzinsuffizienz: Probleme Bei Der Medikamentösen Einstellungunclassified

Stellenwert der Telemedizin in 2011

Zugck

Cebola

Taeger

et al. 2011

Herz

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Heart failure represents a significant clinical and health economic problem. The implementation of new therapeutic strategies favorably affecting the course of the disease remains insufficient in day to day practice. Thus, the use telemedicine offers a central service and information instrument, such that optimized therapy can be achieved by consistent patient surveillance. Predefined vital parameters are automatically transmitted to the telemedicine center; if individually predefined limits are exceeded, therapeutic means are immediately initiated. The service is available to patients 24 h/day throughout the year in case cardio-pulmonary symptoms are experienced. This patient-oriented use of technology should not replace the physician-patient relationship, but improves and supports the participation and self-management of patients.

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“…Die 1-Jahres-Sterblichkeit der Patienten mit chronischer Herzinsuffizienz reicht von ca. 10% bis 50%, abhängig vom Schweregrad der Erkrankung und abhängig von der Umsetzung leitliniengerechter therapeutischer Maßnahmen [12][13][14][15]. Die Herzinsuffizienz war in Deutschland im Jahre 2004 bei Männern die vierthäufigste Todesursache nach KHK, akutem Myokardinfarkt und bösartigen Neubildungen der Bronchien und der Lunge (15 053 Todesfälle).…”

Section: Kardiovaskuläre Erkrankungen In Deutschlandunclassified

“…Durch die medikamentöse Therapie mit ACEHemmern und/oder AT1-Blockern, Beta-Blockern, Diuretika und Aldosteron-Antagonisten wird nicht nur die Leistungsfähigkeit dieser Patienten, sondern auch deren Lebenserwartung signifikant verbessert [12,13,15].…”

Section: Chronische Herzinsuffizienz Evidenzunclassified

Deutsche Leitlinie zur Rehabilitation von Patienten mit Herz-Kreislauferkrankungen (DLL-KardReha)

Bjarnason-Wehrens

Held²,

Hahmann³

et al. 2007

Clin Res Cardiol Suppl

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Beta-blocker treatment of chronic systolic heart failure improves prognosis even in patients meeting one or more exclusion criteria of the MERIT-HF study

Cited by 25 publications

References 12 publications

Are There Any Significant Differences Between Females and Males in the Management of Heart Failure? Gender Aspects of an Elderly Population With Symptoms Associated With Heart Failure

Are There Any Significant Differences Between Females and Males in the Management of Heart Failure? Gender Aspects of an Elderly Population With Symptoms Associated With Heart Failure

Stellenwert der Telemedizin in 2011

Deutsche Leitlinie zur Rehabilitation von Patienten mit Herz-Kreislauferkrankungen (DLL-KardReha)

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