Beta-glucan feeding effect on biochemical and immune responses in vaccinated and non-vaccinated piglets against proliferative enteropathy

Abstract

The aim of this study was to compare the results of active non-specific immuno-modulation in form of feeding food additive based on beta-glucan to pregnant sows and consecutive specific immuno-modulation by vaccination of their sucklings. Experimental sows were fed feedstuff with preparation on basis of beta-glucan at a 5% concentration from day 14 before parturition until the weaning of piglets; control sows were fed standard feedstuff only. Sucklings were vaccinated with a single dose of 2 ml of oral vaccine Enterisol ® Ileitis one week before weaning. Collection of biological material was done 3 × in sows and 5 × in sucklings. Postvaccination examination of blood serum for antibodies against L. intracellularis in sucklings in experimental and control groups was negative, probably due to insufficiently long period of rejection of antibiotics-medicated feedstuff and by chlorinated water. With the exception of immunological profile, no essential changes were recorded in the dynamics of other indices of examined profiles in groups of sows in relation to immune-modulation. In groups of sucklings from sows fed beta-glucan supplemented feedstuff significant changes were determined for various indices compared with sucklings from sows fed standard foodstuff. This is the first similar study in pig herds in Slovakia.

Current use of phytogenic feed additives in animal nutrition: a review

“…These substances are obtained mainly from fungi, Basidiomycetes and yeast of the genus Saccharomyces ceverisiae (Wojcik 2014a); their effects are studied in a number of animal species, e.g. in cattle (Wojcik 2014a, b), sheep (Milewski et al 2013;Zabek et al 2013) or pigs (Sorocinova et al 2013). Beta-glucans can be found in plant components, too, traditionally in the aleuronic layer of barley and oat bran, or seaweed.…”

The effect of Leiber Beta-S on selected immunity indicators in calves

“…The stimulating effects of Leiber Beta-S were significantly less profound than those noted in the author's previous studies on calves whose diets were supplemented with Biolex-Beta HP (Milewski et al 2007) and Biolex MB40 (Wójcik 2010). Higher concentrations of IgG secretion and a significant increase in gamma globulin concentrations compared to control were observed by Wang et al (2008) in an in vitro study of murine spleen lymphocytes after the administration of Astragalan, Lentinan and Ganoderan and by Soročinová et al (2013) in an in vivo study of suckling pigs whose diets were supplemented with β-glucan (Immunol P). In contrast, Hiss and Sauerwein (2003) did not report an increase in specific antibody concentrations in pigs fed with β-1,3/1,6-D-glucan after vaccination against the porcine reproductive and respiratory syndrome.…”