Betamethasone valerate compared with sodium cromoglycate in asthmatic children

Ng, Stolpetskaia; Dash, C. H.; Savage, S.

doi:10.1136/pgmj.53.620.315

Cited by 27 publications

(6 citation statements)

References 8 publications

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“…However, the differences revealed by our study are small in contrast to those of Ng et al (1977) who found a striking superiority of steroid aerosol (BV) over DSCG in equivalent doses to ours. Our study was not designed to comment on their findings that DSCG's effectiveness was mainly confined to daytime.…”

Section: Discussioncontrasting

confidence: 99%

“…Although several authors compare disodium cromoglycate (DSCG) and betamethasone-17-valerate (BV) as treatment for asthma in children (Kuzemko etal.,\ 974;Hiller & Milner, 1975;Ng, Dash & Savage, 1977;Sarsfield & Sugden, 1977) and in adults (Couch, Sutton & Walker, 1977;Dawood, Hendry & Walker, 1977) the only comparison of DSCG with beclomethasone dipropionate (BDP) is a childhood study by Mitchell et al (1976) who found the drugs to be of equal benefit. They indicated the need for further studies.…”

Section: Introductionmentioning

confidence: 99%

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Disodium cromoglycate compared with beclomethasone dipropionate in juvenile asthma

Francis

McEnery

1984

Clin Experimental Allergy

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Summary In a double‐blind controlled crossover trial of inhaled disodium cromoglycate and beclomethasone dipropionate in juvenile asthma, beclomethasone produced higher therapeutic scores but significantly so in only two indices–wheeze‐free days and morning peak flow rates. Combined treatment offered no advantage over beclomethasone alone. No side‐effects were noted. The findings confirm other studies of cromoglycate and a steroid aerosol (betamethasone 17‐valerate) but disagree with the only other comparative trial of cromoglycate and beclomethasone, in which both were found equally effective.

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Section: Discussioncontrasting

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Disodium cromoglycate compared with beclomethasone dipropionate in juvenile asthma

Francis

McEnery

1984

Clin Experimental Allergy

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“…19 -21 Previous studies comparing cromolyn sodium with ICSs in older children have consistently found ICSs to be more effective in controlling symptoms and improving lung function. 10,11,13,14 In this study, asthma control was primarily assessed on the basis of the rate of asthma exacerbations because young children are unable to perform pulmonary function tests adequately and because standard reference values are not available for children who are younger than 5 years. 1 Also, routine assessment of asthma exacerbations is an important measure of long-term asthma control.…”

Section: Discussionmentioning

confidence: 99%

Nebulized Budesonide Inhalation Suspension Compared With Cromolyn Sodium Nebulizer Solution for Asthma in Young Children: Results of a Randomized Outcomes Trial

Leflein¹,

Szefler²,

Murphy³

et al. 2002

Pediatrics

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“…In patients with severe asthma, inhaled corticosteroids are clearly the more effective agents [ 33–35]. On the other hand, in mild‐to‐moderate patients three out of five studies showed comparable efficacy [ 36–38] while only two showed a better response to inhaled corticosteroids [ 39, 40] (and one of these trials was uncontrolled) [ 40].…”

Section: Clinical Comparisonsmentioning

confidence: 99%