Better lung function with increased handgrip strength, as well as maximum oxygen uptake, in congenital heart disease across the lifespan

Smith, Maia P.; Müller, Jan; Neidenbach, Rhoia; Ewert, Peter; Hager, Alfred

doi:10.1177/2047487318816508

Cited by 19 publications

(11 citation statements)

References 42 publications

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“…We further showed that HGS was independently correlated with spirometry. Our results were consistent with previous studies, supporting the conclusion that better respiratory function is associated with greater HGS [13][14][15][29][30][31]. Some studies reported that HGS is a significant predictor of pulmonary function in healthy young adults [32], and some concluded that strength training might improve lung health in adolescents and renal transplant recipients [15,33].…”

Section: Discussionsupporting

confidence: 92%

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

et al. 2020

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Background: Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial. This study analysed pulmonary function and HGS stratified by sex and age in a healthy Chinese Han population, as well as the associations between HGS and pulmonary function parameters. Methods: HGS was measured by a Jamar dynamometer and pulmonary function was tested using a portable spirometer. Frequencies and variables are presented as percentages and means ± standard deviations, respectively. Chi-square tests were used for comparisons of categorical variables, and Student's t-tests or Mann-Whitney U-tests were used for continuous variables. Pearson's correlation coefficients were used to analyse the normally distributed variables, and Spearman correlation coefficients were used to analyse the non-normally distributed variables. Multivariate linear regression models were employed to explore the relationships between HGS and parameters of pulmonary function. The statistical significance was set at p < 0.01. Results: Cross-sectional data were available for 1519 subjects (59.0% females, 57.9 ± 13.3 years old). Males had higher average HGS than females (40.2 vs. 25.0 kg, p < 0.01), as well as better pulmonary function. Both HGS and pulmonary function parameters were significantly inversely correlated with age (r ≤ − 0.30, p < 0.01). The maximum value of vital capacity (VC max), forced expiratory volume in 3 s (FEV 3) and forced vital capacity (FVC) were strongly correlated with HGS among the pulmonary function indices (r = 0.72, 0.70 and 0.69, respectively, p < 0.001). In the multivariate linear regression analysis, HGS and height were positively correlated, while age and pulse pressure were negatively correlated with HGS. In males, the FVC, VC max and FEV3 increased by 0.02 L, 0.023 L and 0.03 L in per 1 kg increase in HGS, respectively. The HGS coefficients for females were smaller than those for males. Conclusions: Both pulmonary function and HGS were inversely correlated with age, and better pulmonary function was associated with greater handgrip strength.

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Section: Discussionsupporting

confidence: 92%

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

et al. 2020

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“…We further showed that HGS was independently correlated with spirometry. Our results were consistent with previous studies, supporting the conclusion that better respiratory function is associated with greater HGS [13][14][15][28][29][30]. Some studies reported that HGS is a significant predictor of pulmonary function in healthy young adults [31], and some concluded that strength training might improve lung health in adolescents and renal transplant recipients [15,32].…”

Section: Discussionsupporting

confidence: 92%

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

Chen

Liu

Wang

et al. 2020

Preprint

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Background: Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial. This study analyzed pulmonary function and HGS stratified by sex and age in a healthy Chinese Han population, as well as the associations between HGS and pulmonary function parameters. Methods: HGS was measured by a Jamar dynamometer and pulmonary function was tested using a portable spirometer. Frequencies and variables are presented as percentages and means ± standard deviations, respectively. Chi-square tests were used for comparisons of categorical variables, and Student’s t-tests or Mann–Whitney U-tests were used for continuous variables. Pearson correlation and multivariate linear regression models were employed to explore the relationships between HGS and parameters of pulmonary function. The statistical significance was set at p <0.01. Results: Cross-sectional data were available for 1519 subjects (59.0% females, 57.9±13.1 years old). Males had higher average HGS than females (40.2 vs 25.0 kg, p <0.01 ), as well as better pulmonary function. Both HGS and pulmonary function parameters were significantly inversely correlated with age (r=-0.30, p < 0.01). Maximum value of vital capacity, forced expiratory volume in 3 second and forced vital capacity were strongly correlated with HGS among the pulmonary function indices (r=0.72, 0.70 and 0.69, respectively, p <0.001). In multivariate linear regression analysis, HGS and height were positively correlated, while age and pulse pressure were negatively correlated with HGS. Conclusions: Both pulmonary function and HGS were inversely correlated with age, and better pulmonary function was associated with greater handgrip strength.

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“…These results are in accordance with the findings of Smith et al as they showed a positive association between strength and exercise capacity. 35 Despite the promising results, it is important to note that the study of Cordina et al included only six patients.…”

Section: Exercise Capacitymentioning

confidence: 98%

Physical exercise training in patients with a Fontan circulation: A systematic review

Scheffers

Berg

Ismailova

et al. 2020

European Journal of Preventive Cardiology

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Background Patients with a Fontan circulation have a reduced exercise capacity, which is an important prognostic predictor of morbidity and mortality. A way to increase exercise capacity in Fontan patients might be exercise training. This systematic review assesses the effects of exercise training investigated in Fontan patients in order to provide an overview of current insights. Design and methods Studies evaluating an exercise training intervention in Fontan patients published up to February 2020 were included in this systematic review. Results From 3000 potential studies, 16 studies reported in 22 publications met the inclusion criteria. In total, 264 Fontan patients with mean age range 8.7–31 years, were included. Different training types including inspiratory muscle training, resistance training and aerobic training were investigated. Main outcome measures reported were peak oxygen uptake, cardiac function, lung function, physical activity levels and quality of life. Peak oxygen uptake increased significantly in 56% of the studies after training with an overall mean increase of +1.72 ml/kg/min (+6.3%). None of the studies reported negative outcome measures related to the exercise programme. In four studies an adverse event was reported, most likely unrelated to the training intervention. Conclusions Exercise training in Fontan patients is most likely safe and has positive effects on exercise capacity, cardiac function and quality of life. Therefore exercise training in Fontan patients should be encouraged. Further studies are required to assess the optimal training type, intensity, duration and long-term effects.

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Better lung function with increased handgrip strength, as well as maximum oxygen uptake, in congenital heart disease across the lifespan

Cited by 19 publications

References 42 publications

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

Physical exercise training in patients with a Fontan circulation: A systematic review

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