The interconnectedness of global economies and workforces have influenced the mobility of people between countries and their career development. Researchers need to consider contextual influences on international career transitions and select a methodology that illuminates peoples’ meaning making of diverse experiences. In this critical review, we reflect on Interpretative Phenomenological Analysis (IPA), through describing the theoretical underpinnings and practical applications, including the seven indications and six contraindications of the IPA process. Overall, IPA seems to have strong applicability for research with people experiencing international career transitions, particularly because of the solid philosophical and human sciences basis, representation of shifts in meaning-making, and consideration of individuals’ unique transition contexts and diverse experiences. Researchers are invited to consider some hesitations in the IPA process, such as challenges in creating deep interpretations in data analysis and distinguishing whose interpretations are represented in the findings. Future research considerations are suggested to advance theoretical and practical applications, including a summary evaluation of the IPA process to inform researchers’ decision-making.