“…The global spatial navigation technique mainly involves computer or robotics-assisted spinal surgery, navigated by macroscopic imaging modalities ( Helm et al, 2015 ; Ahern et al, 2020 ). Since spinal navigation systems allow for either intra-operative imaging or pre-operative imaging with intra-operative updates, conventional navigation paradigms include intra-operative 2D fluoroscopic navigation ( Foley et al, 2001 ), pre-operative CT with manual intra-operative registration ( Nottmeier and Crosby, 2007 ), pre-operative CT with fluoroscopic registration and update, and intra-operative CT or CBCT ( Tian et al, 2011 ; Dea et al, 2016 ; Cool et al, 2021 ; Zhang et al, 2021 ; Felix et al, 2022 ; Tabarestani et al, 2022 ). Common to these solutions is their association with X-ray-like imaging (fluoroscopy or CT-based navigation solutions featuring ionizing radiation), which can harm both patient and surgeon ( Hecht et al, 2018 ; Ahern et al, 2020 ).…”