Transhumanism is a social, technological, political, and philosophical movement that advocates the transformation of human nature by means of pharmacology, genetic manipulation, cybernetic modification, nanotechnology, and a host of other technologies. The aim of this movement is to increase physical and sensory abilities, augment intelligence and memory, and extend lifespan. After providing some background on transhumanism, its philosophical heritage, and its goals, the author looks at three arguments against transhumanism, arguing that they are unpersuasive and should be rejected. This paper presents two arguments against transhumanism that have merit. The first argument is an argument from justice that addresses the distribution of benefits and burdens for funding, developing, and employing enhancement technology. The second argument examines a significant assumption held by many transhumanists, namely, that there is an essential “human nature” that can be transcended.