2018
DOI: 10.1016/j.suronc.2018.02.007
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Beyond T, N and M: The impact of tumor deposits on the staging and treatment of colorectal and gastric carcinoma

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Cited by 20 publications
(19 citation statements)
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“…Many individual studies have reported TDs to be an independent prognostic factor in GC but, to the best of our knowledge, there is no meta‐analysis to group these findings and demonstrate their significance. A recent study which included a review on the impact of TDs in GC highlighted the undeniable prognostic impact of TDs and the need to conform a strategy for staging and treatment. Therefore, our results can only be compared to those in which TDs have been demonstrated to be an independent prognostic factor, such as for CRC.…”
Section: Discussionmentioning
confidence: 99%
“…Many individual studies have reported TDs to be an independent prognostic factor in GC but, to the best of our knowledge, there is no meta‐analysis to group these findings and demonstrate their significance. A recent study which included a review on the impact of TDs in GC highlighted the undeniable prognostic impact of TDs and the need to conform a strategy for staging and treatment. Therefore, our results can only be compared to those in which TDs have been demonstrated to be an independent prognostic factor, such as for CRC.…”
Section: Discussionmentioning
confidence: 99%
“…This concept is crucial for understanding the impact of TDs. In fact, its role as an independent negative prognostic factor seems to be clear both in the presence and absence of lymph node metastases [10]. Unfortunately, most of the studies published so far are retrospective with several limitations which contributed to the lack of consensus.…”
mentioning
confidence: 99%
“…The role of TDs in gastric cancer staging is currently debatable [ 21 ]. In recent decades, of the findings of several reports have supported the concept of TDs being an independent prognostic factor in gastric cancer [ 22 , 23 , 24 ].…”
Section: Discussionmentioning
confidence: 99%
“…The relationship in terms of survival between the presence of TDs and N stage has been evaluated in multiple studies worldwide [ 21 , 23 , 24 , 25 , 27 , 30 , 32 ]. In a Chinese study consisting of 1518 patients [ 30 ], a worse prognosis was found in pN0, pN1, pN2, and pN3a patients with TDs compared to the same subgroups without TDs; however, there was no significant difference between patients with and without TDs in the pN3b subgroup.…”
Section: Discussionmentioning
confidence: 99%