Beyond T2 and 3T: New MRI techniques for clinicians

Knowles, Benjamin R.; Friedrich, F; Fischer, Carola; Paech, Daniel; Ladd, Mark E.

doi:10.1016/j.ctro.2019.04.009

Cited by 10 publications

(8 citation statements)

References 214 publications

(225 reference statements)

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“…More recently, new HP 13 C probe, [1,[3][4][5][6][7][8][9][10][11][12][13] C 2 ]ethyl acetoacetate (EAA), has been reported feasible in imaging the metabolism in rats with implanted HCC. 51 It is generally acknowledged that the concentrations and activities of carboxylesterases, an enzyme that turn EAA to acetoacetate (AA), are lower in cancer cells compared to the corresponding normal cells.…”

Section: Detection Of Early Hccmentioning

confidence: 99%

Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities

Zheng

Song

Lee

et al. 2022

Liver International

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Hyperpolarized carbon‐13 magnetic resonance imaging (HP 13C MRI) is a recently translated metabolic imaging technique. With dissolution dynamic nuclear polarization (d‐DNP), more than 10 000‐fold signal enhancement can be readily reached, making it possible to visualize real‐time metabolism and specific substrate‐to‐metabolite conversions in the liver after injecting carbon‐13 labelled probes. Increasing evidence suggests that HP 13C MRI is a potential tool in detecting liver abnormalities, predicting disease progression and monitoring response treatment. In this review, we will introduce the recent progresses of HP 13C MRI in diffuse liver diseases and liver malignancies and discuss its future opportunities from a clinical perspective, hoping to provide a comprehensive overview of this novel technique in liver diseases and highlight its scientific and clinical potential in the field of hepatology.

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Section: Detection Of Early Hccmentioning

confidence: 99%

Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities

Zheng

Song

Lee

et al. 2022

Liver International

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“…Moreover, imaging techniques are constantly evolving, and the spread of 3T magnets and the advent of ultra-high field MRI (7T) will improve the analysis of tumor metabolism and neuroinflammation. We can cite the use of phosphorous-31 spectroscopy, oxygen-17 imaging, carbon-13, and deuterium spectroscopy or ultrasmall superparamagnetic iron oxide (USPIO) contrast agents [ 83 , 84 , 85 ].…”

Section: Resultsmentioning

confidence: 99%

Pseudoprogression in Glioblastoma: Role of Metabolic and Functional MRI-Systematic Review

et al. 2022

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Background: Glioblastoma is the most frequent malignant primitive brain tumor in adults. The treatment includes surgery, radiotherapy, and chemotherapy. During follow-up, combined chemoradiotherapy can induce treatment-related changes mimicking tumor progression on medical imaging, such as pseudoprogression (PsP). Differentiating PsP from true progression (TP) remains a challenge for radiologists and oncologists, who need to promptly start a second-line treatment in the case of TP. Advanced magnetic resonance imaging (MRI) techniques such as diffusion-weighted imaging, perfusion MRI, and proton magnetic resonance spectroscopic imaging are more efficient than conventional MRI in differentiating PsP from TP. None of these techniques are fully effective, but current advances in computer science and the advent of artificial intelligence are opening up new possibilities in the imaging field with radiomics (i.e., extraction of a large number of quantitative MRI features describing tumor density, texture, and geometry). These features are used to build predictive models for diagnosis, prognosis, and therapeutic response. Method: Out of 7350 records for MR spectroscopy, GBM, glioma, recurrence, diffusion, perfusion, pseudoprogression, radiomics, and advanced imaging, we screened 574 papers. A total of 228 were eligible, and we analyzed 72 of them, in order to establish the role of each imaging modality and the usefulness and limitations of radiomics analysis.

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“…Ultrahigh-field MRI at 7T or higher is expected to be introduced for clinical use in the near future [75,76]. These technical advances likely will improve the amount of anatomical and functional information that can be extracted from tumor images.…”

Section: New Mri Techniquesmentioning

confidence: 99%

Useful MRI Findings for Minimally Invasive Surgery for Early Cervical Cancer

Park

Kim

2021

Cancers

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According to the recent International Federation of Gynecology and Obstetrics (FIGO) staging system, Stage III cervical cancer indicates pelvic or paraaortic lymph node metastasis. Accordingly, the new FIGO stage accepts imaging modalities, such as MRI, as part of the FIGO 2018 updated staging. Magnetic resonance imaging (MRI) is the best imaging modality to estimate the size or volume of uterine cancer because of its excellent soft tissue contrast. As a result, MRI is being used increasingly to determine treatment options and follow-up for cervical cancer patients. Increasing availability of cancer screening and vaccination have improved early detection of cervical cancer. However, the incidence of early cervical cancers has increased compared to that of advanced cervical cancer. A few studies have investigated if MRI findings are useful in management of early cervical cancer. MRI can precisely predict tumor burden, allowing conization, trachelectomy, and simple hysterectomy to be considered as minimally invasive treatment options for early cervical cancer. This imaging modality also can be used to determine whether there is recurrent cancer following minimally invasive treatments. The purpose of this review is to highlight useful MRI features for managing women with early cervical cancer.

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Beyond T2 and 3T: New MRI techniques for clinicians

Cited by 10 publications

References 214 publications

Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities

Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities

Pseudoprogression in Glioblastoma: Role of Metabolic and Functional MRI-Systematic Review

Useful MRI Findings for Minimally Invasive Surgery for Early Cervical Cancer

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