v n }, be a simple connected graph with n vertices, m edges and vertex degree sequence d 1 ≥ d 2 ≥ • • • ≥ d n > 0, d i = d(v i). General zeroth-order Randić index of G is defined as 0 R α (G) = ∑ n i=1 d α i , and general sum-connectivity index as χ α (G) = ∑ i∼ j (d i + d j) α , where α is an arbitrary real number. In this paper we establish a relationship between 0 R α+β (G), 0 R α−β (G) and 0 R α (G), as well as χ α+β (G), χ α−β (G) and χ α (G), where α and β are arbitrary real numbers. By the appropriate choice of parameters α and β , a number of new/old inequalities that reveal relationships between various vertex and edge degree-based topological indices are obtained.