2006
DOI: 10.1016/j.rvsc.2006.01.004
|View full text |Cite
|
Sign up to set email alerts
|

BHV-1 vaccine induces cross-protection against BHV-5 disease in cattle

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

2
47
0
6

Year Published

2007
2007
2018
2018

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 45 publications
(55 citation statements)
references
References 41 publications
2
47
0
6
Order By: Relevance
“…BoHV-1 and -5 show extensive serological cross-reactivity so that they cannot be distinguished by routine virus neutralization tests (32). In addition, it has been demonstrated that a BoHV-1 vaccine induced partial protection against a BoHV-5 virulent challenge in calves (13,14). Thus, the recombinants BoHV-5 gE∆, TK∆ and gE/TK∆ described herein represent potential vaccine candidates to prevent BoHV-1 and -5 associated diseases in South American countries.…”
Section: Discussionmentioning
confidence: 93%
See 2 more Smart Citations
“…BoHV-1 and -5 show extensive serological cross-reactivity so that they cannot be distinguished by routine virus neutralization tests (32). In addition, it has been demonstrated that a BoHV-1 vaccine induced partial protection against a BoHV-5 virulent challenge in calves (13,14). Thus, the recombinants BoHV-5 gE∆, TK∆ and gE/TK∆ described herein represent potential vaccine candidates to prevent BoHV-1 and -5 associated diseases in South American countries.…”
Section: Discussionmentioning
confidence: 93%
“…Most of the vaccines marketed in South America contain inactivated BoHV-1 strains, which are not effective with respect to the cell immune response (13,14), and lack a serological marker, which is an important criterion for vaccination with differential vaccines (15). Some European countries have successfully eradicated BoHV-1 infection based on differential vaccines (12).…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…BoHV-1 and BoHV-5 are closely related genetically, antigenically and display an extensive serological cross-reactivity (Bratanich et al 1991, Vogel et al 2002, Delhon et al 2003, Del Medico Zajac et al 2006. Bovine herpesvirus type 1 is distributed worldwide -with the exception of some European countries that eradicated the infection -and is associated with a variety of clinical conditions, including respiratory disease (infectious bovine rhinotracheitis, IBR), reproductive system disease (vulvovaginitis or balanopostitis IPV/IBP) and abortions (Kahrs 2001).…”
Section: Introductionmentioning
confidence: 99%
“…Few vaccines contain BoHV-5 antigens in their formulation, none of them based on live virus (E.F. Flores, unpublished). The antigenic similarity and serological cross-reactivity between BoHV-1 and -5 has led to the assumption that vaccines containing either virus would confer protection upon homologous and heterologous virus challenge (Del Medico Zajac et al 2006, Brum et al 2010a, Anziliero et al 2011. Following the trend of North America and Europe, South American countries are now embarking on the development and use of BoHV-1 DIVA (for differentiating infected from vaccinated animals) vaccines (Brum et al 2010a).…”
Section: Introductionmentioning
confidence: 99%