BI-RADS sınıflaması meme kanseri risk faktörlerini ne oranda karşılar ve hematolojik parametrelerle ilişkisi nedir?

Abstract

Aim:The mass found in the breast brings to mind the most common breast cancer in women. However, it is important to make a correct diagnosis of whether the breast masses are benign. The most commonly used imaging method in the diagnosis of these masses is mammography. The use of the Breast Imaging Reporting and Data System (BI-RADS) is known to be useful in distinguishing whether the masses are benign or malignant. In this study, we aimed to find out to what extent the BI-RADS classification meets breast cancer risk factors and its relation with hematological parameters.Methods: A total of 380 women who were admitted to our hospital's breast and endocrine surgery outpatient clinic with complaints of breast disease and who were operated on after a mammography examination (with suspicion and /or diagnosis of breast cancer) were included. In this retrospective cohort study, women were asked about their age, height, weight, educational status, marital status, and first menstrual age. In addition, it was asked whether she had menstruation, whether she was pregnant or not, the number of pregnancies (if she got pregnant), whether she had a family history of breast cancer, whether she was using a contraceptive pill or hormone replacement therapy (HRT).Results: Among the risk factors of breast cancer, patient age is ≥51 (OR 3.1, 95% CI 1.6-6.1), body mass index (BMI) is ≥27.88 kg / m2 (OR 2.7, 95% CI 1.4-5.2), the first gestational age is ≥30. (OR 2.8, 95% CI 1.4-5.8), the number of non-full-term pregnancies (OR 4.4, 95% CI 1.7-11.2), and having dense breast tissue (OR 5.0, 95% CI 2.6-9.7) BI-RADS 4-5-6 found to increase reporting and increased risk of breast cancer. It found that women with neutrophil leukocyte/lymphocyte ratio (NLR) 2.19 and platelet/lymphocyte ratio (PLR) 146.81 and above had a significantly higher reporting of mammograms as BI-RADS 5-6 (p <0.000, p <0.000, respectively). Conclusion:Breast cancer increases with increasing age and BMI. The risk of breast cancer is high in women with dense breast tissue, who give birth at an older age and high who have a low or abortion number. BI-RADS classification is very useful in distinguishing whether breast masses are benign or malignant and important in determining breast density from breast cancer risk factors.