Biased Genotype Distributions of Candida albicans Strains Associated with 649 Clinical Vulvovaginal Candidiasis in China

Pang, Qiuyu; Liu, Weida; Cui, Fan; Kan, Siyue; Li, Xiaofang

doi:10.1007/s11046-022-00671-4

Cited by 2 publications

(1 citation statement)

References 40 publications

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“…In addition to the widely studied bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) has been a hot topic, which is a multifactor infectious disease of women's lower reproductive tract, mainly caused by Candida albicans, resulting in pathological inflammation (Farr et al, 2021). In a study that collected 649 separate strains of VVC patients in China, researchers found that Candida albicans was the dominant pathogen of VVC, but the proportion of non-Candida albicans infection was also increasing (Pang et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy

Sun

Qiu

et al. 2023

Front. Cell. Infect. Microbiol.

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Vaginal microbiome is mutually beneficial to the host and has a significant impact on health and disease. Candida species, including Candida albicans, are part of the mucosal flora of most healthy women. Under suitable conditions, they can live in the vulvovaginal mucosa, resulting in symptomatic vulvovaginal candidiasis (VVC). Based on the analysis of 16S ribosomal RNA gene sequences, great progress has been made in exploring the composition and structure of vaginal bacterial community. Moreover, researchers have conducted several studies on whether vaginal microbiome will change during VVC infection. In addition, it has been reported that vaginal colonization of probiotics in vaginal microorganisms, especially Lactobacillus, can effectively reduce the risk of VVC and treat VVC. This review aims to summarize the changes of vaginal microflora during VVC infection, and further point out the possibility of using lactic acid bacteria as probiotics to treat VVC, so as to reduce the adverse consequences of VVC infection and reduce the expensive treatment cost.

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Section: Introductionmentioning

confidence: 99%

Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy

Sun

Qiu

et al. 2023

Front. Cell. Infect. Microbiol.

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Research progress of hydrogels in the prevention of pelvic inflammatory disease

Xiao,

Ma,

et al. 2024

MedComm – Biomaterials and Applications

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Pelvic inflammatory disease (PID) is a critical global health concern with the potential to lead to adverse outcomes, including infertility and chronic pelvic pain. Since PID is often caused by ascending vaginal infections or urinary tract infections, understanding the treatment of both is critical to preventing PID. Meanwhile, the emergence of drug‐resistant and persistently infected strains poses a growing challenge. This review discusses current clinical treatments for the prevention of PID from the physiologic basis of PID, as well as summarizes the advantages and research progress of hydrogels in the prevention of PID. In contrast to conventional treatments, hydrogels serve as excellent vehicles for vaginal drug delivery, maintaining the presence of the drug at the target site and controlling its release. In the context of urinary tract infections (UTIs), hydrogels are employed primarily as coatings on catheters to prevent and treat catheter‐associated UTIs. Finally, this review summarizes the limitations of hydrogels in PID prevention and future directions for development with the aim of elucidating avenues for clinical treatment of PID and informing further research.

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Biased Genotype Distributions of Candida albicans Strains Associated with 649 Clinical Vulvovaginal Candidiasis in China

Cited by 2 publications

References 40 publications

Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy

Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy

Research progress of hydrogels in the prevention of pelvic inflammatory disease

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