Bibliometric Analysis of Zinc and Bone

Abstract

Background: Zinc plays a crucial role in bone health; however, there is a lack of bibliometric analysis on zinc and bone research. This study aims to fill this research gap by conducting a bibliometric analysis of the development and research focus of zinc and bone-related studies. Methods: We performed a search in the Web of Science Core Collection and selected relevant literature on zinc and bone. We then conducted statistical analysis and visualized the literature to reveal the development trends and key areas of zinc and bone research. Results: From the retrieved literature, we observed an increasing trend in zinc and bone-related research since the 1990s. China emerged as a core country in research related to zinc and bone, with Shanghai Jiao Tong University being the institution with the greatest influence in this field. Yamaguchi, M emerged as the author with the greatest influence in research related to zinc and bone. These studies mainly focused on the role of zinc in bone formation, bone density and quality, bone diseases, and bone tissue engineering. Conclusion: Research on zinc and bone is growing, and there is increasing interest in the role of zinc in bone health. Future research should focus on gaining a deeper understanding of the toxicity and safety of zinc-based biomaterials, optimizing material design to improve biocompatibility and functionality, investigating the mechanisms of bio-interactions, and expanding the application areas of zinc-based biomaterials to drive their development in clinical and biomedical settings.