Bibliometric and visualized analysis of ocular drug delivery from 2001 to 2020

Peng, Cheng; Kuang, Liangju; Zhao, Jiangyue; Ross, Amy E.; Wang, Zhongqing; Ciolino, Joseph B.

doi:10.1016/j.jconrel.2022.03.031

Cited by 103 publications

(66 citation statements)

References 160 publications

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“…However, a comprehensive and intuitive analysis of the evolution and trend of HA in the treatment of OA by a bibliometric analysis is still lacking. Bibliometric analysis is an important quantitative analysis method for the published papers on a specific topic, which has been widely used in various fields, including mathematics, artificial intelligence, economics and clinical medicine ( Chen et al, 2021 ; Gurnani and Kaur, 2021 ; Peng et al, 2022 ). In this study, we used a bibliometric approach to scientifically quantify and quantitatively analyze published articles on HA for the treatment of OA in the WoSCC database from 1 January 2002 to 31 December 2021.…”

Section: Introductionmentioning

confidence: 99%

Harnessing hyaluronic acid for the treatment of osteoarthritis: A bibliometric analysis

Zhang

Lin

Huang

et al. 2022

Front. Bioeng. Biotechnol.

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Background: Osteoarthritis (OA) is a common disease which usually occurs in middle-aged and elderly people. Hyaluronic acid (HA) has been widely used to treat OA and related researches on the efficacy and safety of HA in the treatment of OA have been published. Therefore, the purpose of this research was to investigate the subject characteristics of harnessing HA for the treatment of OA and to analyse the relevant trends and hotspots by using a bibliometric approach.Methods: The articles published from 1 January 2002 to 31 December 2021 were searched in the Web of Science Core Collection (WoSCC) and the relevant information of HA for the treatment of OA was extracted after screening. Then, a total of 2438 publications were analysed by using Microsoft Excel, CiteSpace 5.8.R3, VOSviewer 1.6.18 and the Online Analysis Platform of Literature Metrology (http://bibliometric.com/).Results: A total of 2438 articles were finally included for analysis. The number of publications increased year by year. A total of 83 coutries and 3319 institutions published 2438 manuscripts in the field of use HA for the treatment of OA. The most productive country was United States with total 689 publications and League of European Research Universities Leru (Belgium) was the leading institution with total 126 publicatios. In terms of authors, the most prominent author was KrausVB, who published 28 papers with the highest H-index (19). In addition, Osteoarthritis and Cartilage had the highest number of publications (152 articles) and the highest number of citations (6450 citations). The co-cited references analysis indicated that the article published by McAlindon in 2014 had the most highest number of citations (91co-citations). What’s more, most research hotspots focused on the efficacy and safety of HA, and regenerative medicine researches such as platelet-rich plasma (PRP) and mesenchymal stem cells (MSCs) have attracted more and more attentions of researchers.Conclusion: This study visually analyzed the historical evolution and future trends of HA for the treatment of OA, and discussed the research priorities. At present, there are still different views on the efficacy of HA for the treatment of OA. Gradually, research hotspots of this field have focused on the regenerative medicine.

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Section: Introductionmentioning

confidence: 99%

Harnessing hyaluronic acid for the treatment of osteoarthritis: A bibliometric analysis

Zhang

Lin

Huang

et al. 2022

Front. Bioeng. Biotechnol.

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“…The clustered keywords in Clusters 1–4 reflect the four research hot spots in this field. For Cluster 1 (nanoparticulate systems for delivering drugs with anti-SARS-CoV-2 activity), typical keywords included: “nanoparticles,” “inhibition,” “drug-delivery,” and “antiviral activity.” For Cluster 2, (nanotechnology for rapid and quantitative SARS-CoV-2 detection), typical keywords included: “gold nanoparticles,” “diagnosis,” “rapid detection,” and “biosensor.” For Cluster 3 (nanovaccines against SARS-CoV-2 delivered by lipid nanoparticles), typical keywords included: “COVID-19,” “nanotechnology,” “vaccine,” and “lipid nanoparticles.” For Cluster 4 (screening antibodies for SARS-CoV-2 neutralization on the basis of viral structure), typical keywords included: “SARS-CoV-2,” “coronavirus,” “spike protein,” and “antibodies.” The closed-loop network suggested that the four hot spots could have overlap [47] . Furthermore, according to the data shown in Fig.…”

Section: Keyword Co-occurrencementioning

confidence: 99%

Mapping the intersection of nanotechnology and SARS-CoV-2/COVID-19: A bibliometric analysis

Zhang¹,

Guo²,

Huang³

et al. 2022

Infectious Medicine

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“…Discussion on this area is beyond the scope of this paper. Comprehensive reviews by Akhter et al and others ( Akhter et al, 2022 ; Peng et al, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Brain-Derived Neurotrophic Factor-Mediated Neuroprotection in Glaucoma: A Review of Current State of the Art

et al. 2022

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Retinal ganglion cells (RGCs) are neurons of the visual system that are responsible for transmitting signals from the retina to the brain via the optic nerve. Glaucoma is an optic neuropathy characterized by apoptotic loss of RGCs and degeneration of optic nerve fibers. Risk factors such as elevated intraocular pressure and vascular dysregulation trigger the injury that culminates in RGC apoptosis. In the event of injury, the survival of RGCs is facilitated by neurotrophic factors (NTFs), the most widely studied of which is brain-derived neurotrophic factor (BDNF). Its production is regulated locally in the retina, but transport of BDNF retrogradely from the brain to retina is also crucial. Not only that the interruption of this retrograde transport has been detected in the early stages of glaucoma, but significantly low levels of BDNF have also been detected in the sera and ocular fluids of glaucoma patients, supporting the notion that neurotrophic deprivation is a likely mechanism of glaucomatous optic neuropathy. Moreover, exogenous NTF including BDNF administration was shown reduce neuronal loss in animal models of various neurodegenerative diseases, indicating the possibility that exogenous BDNF may be a treatment option in glaucoma. Current literature provides an extensive insight not only into the sources, transport, and target sites of BDNF but also the intracellular signaling pathways, other pathways that influence BDNF signaling and a wide range of its functions. In this review, the authors discuss the neuroprotective role of BDNF in promoting the survival of RGCs and its possible application as a therapeutic tool to meet the challenges in glaucoma management. We also highlight the possibility of using BDNF as a biomarker in neurodegenerative disease such as glaucoma. Further we discuss the challenges and future strategies to explore the utility of BDNF in the management of glaucoma.

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Bibliometric and visualized analysis of ocular drug delivery from 2001 to 2020

Cited by 103 publications

References 160 publications

Harnessing hyaluronic acid for the treatment of osteoarthritis: A bibliometric analysis

Harnessing hyaluronic acid for the treatment of osteoarthritis: A bibliometric analysis

Mapping the intersection of nanotechnology and SARS-CoV-2/COVID-19: A bibliometric analysis

Brain-Derived Neurotrophic Factor-Mediated Neuroprotection in Glaucoma: A Review of Current State of the Art

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