Biclonal myeloma in renal failure

Sera from patients with multiple myeloma usually display a single monoclonal immunoglobulin band on serum protein immunofixation electrophoresis. Multiple bands may be seen if the myeloma is bi- or triclonal or if the monoclonal immunoglobulin has rheumatoid factor activity. We describe a patient with light chain–predominant IgA lambda myeloma; the patient’s serum displayed 2 spatially distinct bands reacting for alpha heavy and lambda light chains. The methods used to establish monoclonality are addressed.

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Biclonal myeloma in renal failure

Abstract: DiMitrios vasileiou 2 , boris bogov 2 , ruMiana Krasteva 2 , evgeni haDJiev 2 , gergana tsvetKova 2 , Cvetelina vasileva 2 , niKolai houbanov 2

Cited by 2 publications

References 10 publications

Aberrant ENPP2 expression promotes tumor progression in multiple myeloma

Aberrant ENPP2 expression promotes tumor progression in multiple myeloma

Analysis of Multiple Bands on Serum Protein Immunofixation Electrophoresis: Challenge in Interpretation of Clonality in a Patient with Light Chain–Predominant Multiple Myeloma

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