Bidirectional Relationships Between Weight Change and Sleep Apnea in a Behavioral Weight Loss Intervention

Kline, Christopher E.; Burke, Lora E.; Sereika, Susan M.; Imes, Christopher C.; Rockette‐Wagner, Bonny; Méndez, Dara D.; Strollo, Patrick J.; Zheng, Yaguang; Rathbun, Stephen L.; Chasens, Eileen R.

doi:10.1016/j.mayocp.2018.04.026

Cited by 22 publications

(18 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As noted in our previous work using these data, a significant percentage of the participants had undiagnosed OSA at baseline [ 19 ]. Separate analyses (not shown) were conducted on the subset of participants with OSA data.…”

Section: Methodssupporting

confidence: 52%

Bidirectional relationship between sleep and sedentary behavior in adults with overweight or obesity: A secondary analysis

et al. 2021

Self Cite

View full text Add to dashboard Cite

Objective The relationships between daytime sedentary behavior and that night’s sleep and sleep and next day’s sedentary behavior are unknown. The purpose of this analysis was to examine these potentially bidirectional associations. Methods This study was a secondary analysis of baseline data from an ecological momentary assessment study to determine the triggers for dietary lapses during a weight loss intervention. Sedentary behavior, physical activity, and sleep were objectively measured using accelerometers. Linear mixed modeling was used to examine the bidirectional multivariate associations between activity and sleep characteristics for each outcome examined separately. The models included sex, age, BMI, education, and day of the week (weekday versus weekend). Results Participants were predominantly white (81.5%) and female (88.9%) with a mean age of 51.2 ± 10.6 years. Longer previous night’s total sleep time (b = -0.320, SE = 0.060; p < .001 and being a weekend (b = -63.845, SE = 9.406; p < .001) were associated with less sedentary time the next day. More daytime sedentary time was associated with less wake after sleep onset (b = -0.018, SE = 0.008; p = .016), fewer awakenings (b = -0.010, SE = 0.004; p = .016), and less total sleep time (b = -0.060, SE = 0.028; p = .029) that night. Conclusions The bidirectional relationships between sedentary time and sleep characteristics are complex and may vary depending on participant characteristics and duration of sedentary and sleep time. Interventions to decrease sedentary behavior may benefit by targeting sleep duration and weekday activity.

show abstract

Section: Methodssupporting

confidence: 52%

Bidirectional relationship between sleep and sedentary behavior in adults with overweight or obesity: A secondary analysis

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…In this sample, we previously reported that OSA was associated with worse weight loss in the context of a behavioral weight loss intervention. 25 For these analyses, valid baseline or 6-month AHI data (i.e., ≥2 hours of recording time) were available for 117 participants.…”

Section: Methodsmentioning

confidence: 99%

“…Because OSA is associated with worse sleep 43 and we previously reported that OSA is associated with blunted weight loss, 25 we also explored whether OSA severity accounted for any associations observed between sleep health and weight change. In the subsample with valid AHI data ( n =117), AHI at the beginning of each interval was added as a covariate to the models noted above.…”

Section: Methodsmentioning

confidence: 99%

“… 16 – 23 These limitations are notable because self-reported sleep is often divergent from objectively assessed sleep, 24 sleep may improve following weight loss, 19 and OSA may account for blunted weight loss. 25 Addressing these limitations may provide better insight into the influence of sleep in behavioral weight loss interventions.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The association between sleep health and weight change during a 12-month behavioral weight loss intervention

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background: Prior research on the relationship between sleep and attempted weight loss failed to recognize the multidimensional nature of sleep. We examined the relationship between a composite measure of sleep health and change in weight and body composition among adults in a weight loss intervention. Methods: Adults ( N =125) with overweight or obesity (50.3±10.6 years, 91% female, 81% white) participated in a 12-month behavioral weight loss intervention, with assessments of sleep, weight, fat mass, and fat-free mass at baseline, 6 months, and 12 months. Six sleep dimensions (regularity, satisfaction, alertness, timing, efficiency, and duration) were categorized as ‘good’ or ‘poor’ using questionnaires and actigraphy. A composite score was calculated by summing the number of ‘good’ dimensions. Obstructive sleep apnea (OSA) was assessed in a subsample ( n =117), using the apnea-hypopnea index (AHI) to determine OSA severity. Linear mixed modeling was used to examine the relationships between sleep health and outcomes of percent weight, fat mass, or fat-free mass change during the subsequent 6-month interval, adjusting for age, sex, bed partner, and race; an additional model adjusted for AHI. Results: Mean baseline and 6-month sleep health was 4.5±1.1 and 4.5±1.2, respectively. Mean weight, fat mass, and fat-free mass changes from 0–6 months were −9.3±6.1%, −16.9±13.5%, and −3.4±3.4%, respectively, and 0.4±4.8%, −0.3±10.3%, and 0.7±4.1% from 6–12 months. Better sleep health was associated with greater subsequent weight loss ( P =.016) and fat loss ( P =.006), but not fat-free mass loss ( P =.232). Following AHI adjustment, the association between sleep health and weight loss was attenuated ( P =.102) but remained significant with fat loss ( P =.040). Regularity, satisfaction, timing, and efficiency were each associated with weight and/or fat loss ( P ≤.041). Conclusions: Better sleep health was associated with greater weight and fat loss, with associations attenuated after accounting for OSA severity. Future studies should explore whether improving sleep health, OSA, or the combination improves weight loss.

show abstract

“…Effective weight loss that is maintained has lasting beneficial effects on energy metabolism, and helps to prevent adverse metabolic and cardiovascular events [91]. Lifestyle modification in patients with OSA and diabetes has multiple benefits including weight reduction and improvements in both severity of OSA and glucose control [92].…”

Section: Treatmentmentioning

confidence: 99%

Metabolic Consequences of Obstructive Sleep Apnea Especially Pertaining to Diabetes Mellitus and Insulin Sensitivity

Song

Narla

et al. 2019

Diabetes Metab J

View full text Add to dashboard Cite

Obstructive sleep apnea (OSA) and diabetes has been known to be closely related to each other and both diseases impact highly on the public health. There are many evidence of reports that OSA is associated with diabetes with a bidirectional correlation. A possible causal mechanism of OSA to diabetes is intermittent hypoxemia and diabetes to OSA is microvascular complication. However, OSA and diabetes have a high prevalence rate in public and shares the common overlap characteristic and risk factors such as age, obesity, and metabolic syndrome that make it difficult to establish the exact pathophysiologic mechanism between them. In addition, studies demonstrating that treatment of OSA may help prevent diabetes or improve glycemic control have not shown convincing result but have become a great field of interest research. This review outlines the bidirectional correlation between OSA and diabetes and explore the pathophysiologic mechanisms by approaching their basic etiologies.

show abstract

Bidirectional Relationships Between Weight Change and Sleep Apnea in a Behavioral Weight Loss Intervention

Cited by 22 publications

References 35 publications

Bidirectional relationship between sleep and sedentary behavior in adults with overweight or obesity: A secondary analysis

Bidirectional relationship between sleep and sedentary behavior in adults with overweight or obesity: A secondary analysis

The association between sleep health and weight change during a 12-month behavioral weight loss intervention

Metabolic Consequences of Obstructive Sleep Apnea Especially Pertaining to Diabetes Mellitus and Insulin Sensitivity

Contact Info

Product

Resources

About