Bifidobacterium longum-fermented Broccoli Supernatant Inhibited the Growth of Candida albicans and Some Pathogenic Bacteria in vitro

Suido, Hirohisa; Miyao, Manabu

doi:10.4265/bio.13.41

Cited by 7 publications

(5 citation statements)

References 23 publications

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“…B. longum BB536 or L. pentosus Vege-Start were added to broccoli medium, cultured in an anaerobic environment, then centrifuged and filtered to obtain B. longum fermented broccoli (BFB) and L. pentosus fermented broccoli (LFB). They were found to have inhibitory activities against Candida albicans (Suido and Miyao, 2008). Anti-inflammatory mechanism of Kea (Created with BioRender.com).…”

Section: Fermentation Of Broccoli Supernatant By Bifidobacterium Long...mentioning

confidence: 99%

“…For example, broccoli aptamers function as fluorescent RNA aptamers that unite fluorescent dye and generate fluorescence, providing a convenient method to visualize intrinsic RNA in cells ( Chandler et al., 2018 ). Candida albicans and other bacteria are inhibited by the supernatant of fermented broccoli produced by Bifidobacterium longum and Lactobacillus ( Suido and Miyao, 2008 ). In order to provide some reference materials for the development and utilization of broccoli stalk and leaf resources, this paper will review the distribution of broccoli resources and its stalk and leaf utilization, the types, effects, and mechanisms of action of bioactive substances, and advanced technologies for the development and utilization of broccoli.…”

Section: Introductionmentioning

confidence: 99%

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Research progress on the utilization technology of broccoli stalk, leaf resources, and the mechanism of action of its bioactive substances

et al. 2023

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Broccoli is a nutritious vegetable. It is high in protein, minerals, and vitamins. Also, it possesses antioxidant activities and is beneficial to the human body. Due to its active effect, broccoli is widely accepted by people in daily life. However, in terms of current utilization, only its florets are consumed as vegetables, while more than half of its stalks and leaves are not utilized. The stalks and leaves contain not only nutrients but also bioactive substances with physiologically regulating properties. Therefore research into the action and mechanism of its bioactive substances as well as its development and utilization technology will make contributions to the further promotion of its resource development and utilization. As a theoretical foundation for the resource utilization of broccoli stalks and leaves, this report will review the distribution and consumption of broccoli germplasm resources, the mechanism of action of bioactive substances, and innovative methods for their exploitation.

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Section: Fermentation Of Broccoli Supernatant By Bifidobacterium Long...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Research progress on the utilization technology of broccoli stalk, leaf resources, and the mechanism of action of its bioactive substances

et al. 2023

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“…For example, as a daily oral care preparation, it can prevent the growth of C . albicans in human oral cavity [ 59 ].…”

Section: Antagonistic Microbes Against C Albicansmentioning

confidence: 99%

Biocontrol of Candida albicans by Antagonistic Microorganisms and Bioactive Compounds

Jin

Zhang

et al. 2022

Antibiotics

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Candida albicans is an endogenous opportunistic pathogenic fungus that is harmless when the host system remains stable. However, C. albicans could seriously threaten human life and health when the body’s immune function declines or the normal flora is out of balance. Due to the increasing resistance of candidiasis to existing drugs, it is important to find new strategies to help treat this type of systemic fungal disease. Biological control is considered as a promising strategy which is more friendly and safer. In this review, we compare the bacteriostatic behavior of different antagonistic microorganisms (bacteria and fungi) against C. albicans. In addition, natural products with unique structures have attracted researchers’ attention. Therefore, the bioactive nature products produced by different microorganisms and their possible inhibitory mechanisms are also reviewed. The application of biological control strategies and the discovery of new compounds with antifungal activity will reduce the resistance of C. albicans, thereby promoting the development of novel diverse antifungal drugs.

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“…Bifidobacterium supernatant contains a variety of active substances, including polysaccharides [24], proteins [25], and fatty acids [26]. These ingredients have antioxidation, immune regulation, and other antiaging effects [25,27,28]. Bifidobacterium supernatant can also reverse D-gal-induced organ aging and decrease memory in aging rats [29].…”

Section: Introductionmentioning

confidence: 99%

Bifidobacterium lactis BB-12 Attenuates Macrophage Aging Induced by D-Galactose and Promotes M2 Macrophage Polarization

Zhang

Pan

et al. 2019

Journal of Immunology Research

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Immunosenescence comprises a set of dynamic changes occurring in innate and adaptive immune systems, and macrophage aging plays an important role in innate and adaptive immunosenescence. However, function and polarization changes in aging macrophages have not been fully evaluated, and no effective method for delaying macrophage senescence is currently available. The results of this study reveal that D-galactose (D-gal) can promote J774A.1 macrophage senescence and induce macrophage M1 polarization differentiation. Bifidobacterium lactis BB-12 can significantly inhibit J774A.1 macrophage senescence induced by D-gal. IL-6 and IL-12 levels in the BB-12 groups remarkably decreased compared with that in the D-gal group, and the M2 marker, IL-10, and Arg-1 mRNA levels increased in the BB-12 group. BB-12 inhibited the expression of p-signal transducer and activator of transcription 1 (STAT1) and promoted p-STAT6 expression. In summary, the present study indicates that BB-12 can attenuate the J774A.1 macrophage senescence and induce M2 macrophage polarization, thereby indicating the potential of BB-12 to slow down immunosenescence and inflamm-aging.

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Bifidobacterium longum-fermented Broccoli Supernatant Inhibited the Growth of Candida albicans and Some Pathogenic Bacteria in vitro

Cited by 7 publications

References 23 publications

Research progress on the utilization technology of broccoli stalk, leaf resources, and the mechanism of action of its bioactive substances

Research progress on the utilization technology of broccoli stalk, leaf resources, and the mechanism of action of its bioactive substances

Biocontrol of Candida albicans by Antagonistic Microorganisms and Bioactive Compounds

Bifidobacterium lactis BB-12 Attenuates Macrophage Aging Induced by D-Galactose and Promotes M2 Macrophage Polarization

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