Bifidobacterium longum HY8004 attenuates TNBS-induced colitis by inhibiting lipid peroxidation in mice

Abstract

B. longum HY8004 can improve colitis via the inhibition of lipid peroxidation as well as NF-kappaB activation.

Lactobacillus helveticus HY7801 ameliorates vulvovaginal candidiasis in mice by inhibiting fungal growth and NF-κB activation

“…The common LAB genera are Lactobacillus sp., Lactococcus sp., Leuconostoc sp., Pediococcus sp., Enterococcus sp., Streptococcus sp., and Bifidobacterium sp isolated from fermented foods and intestinal microflora. These LAB are safe microorganisms that improve any disturbances of indigenous microflora [9,10], ameliorate the development of beneficial microflora [7], have anti-inflammatory (anticolitic and antivaginitic) effects [11][12][13], and induce non-specific activation of the host immune system [10]. Furthermore, some Lactobacillus strains isolated from the vaginal cavities of healthy women antagonize C. albicans by lowering the pH and/or producing metabolites, such as hydrogen peroxide and lactic acid, and antibacterial molecules, including bacteriocins [14,15].…”

Lactobacillus johnsonii HY7042 ameliorates Gardnerella vaginalis-induced vaginosis by killing Gardnerella vaginalis and inhibiting NF-κB activation

“…The common LAB genera are Lactobacillus sp., Lactococcus sp., Leuconostoc sp., Pediococcus sp., Enterococcus sp., Streptococcus sp., and Bifidobacterium sp., which can be isolated from fermented foods and intestinal microflora. These LAB are safe microorganisms that improve any disturbances of indigenous microflora [13,14], ameliorate the ill effects of harmful microflora [11], have anti-inflammatory (anticolitic and antivaginitic) effects [15][16][17], and induce the non-specific activation of the host immune system [14]. Furthermore, some Lactobacillus strains isolated from the vaginas of healthy women antagonize vaginosis-associated G. vaginalis by lowering of the pH and/or by producing metabolites, such as, hydrogen peroxide, lactic acid, and antibacterial molecules, including bacteriocins [18,19].…”

Bojanggunbi-tang, a traditional Korean herbal prescription, ameliorates colonic inflammation induced by dextran sulfate sodium and 2,4,6-trinitrobenzene sulfonic acid in mice

“…In the current results, a positive control, sulfasalazine did not show the significance. It has been reported that sulfasalazine has effects on IBD and used in IBD animal experiments as positive control (Lee et al, 2010b;Zhao et al, 2010). We thought the reason why sulfasalazine showed no significant effect in DSS model may be come from different mice strain, dosage, DSS concentration and period of observation (Singh et al, 2009;Lee et al, 2010b).…”