2016
DOI: 10.1016/j.jhep.2015.08.020
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Bifidobacterium pseudocatenulatum CECT7765 induces an M2 anti-inflammatory transition in macrophages from patients with cirrhosis

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Cited by 34 publications
(30 citation statements)
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“…Studies have reported that gut microbiota play an important role in shaping the Treg/Th17 axis in adaptive immune response ( 69 ). Alba et al demonstrated the efficacy of Bifidobacterium for the treatment of patients with cirrhosis through inducing a morphologic, phenotypic and functional transition towards an anti-inflammatory profile ( 70 ). Rui Yu et al investigated two Bifidobacterium.…”
Section: Discussionmentioning
confidence: 99%
“…Studies have reported that gut microbiota play an important role in shaping the Treg/Th17 axis in adaptive immune response ( 69 ). Alba et al demonstrated the efficacy of Bifidobacterium for the treatment of patients with cirrhosis through inducing a morphologic, phenotypic and functional transition towards an anti-inflammatory profile ( 70 ). Rui Yu et al investigated two Bifidobacterium.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, it has been suggested that probiotics can potentially influence equilibrium of commensal and pathogenic bacteria, and thereby destroy homeostasis in inflammatory conditions[13]. Moreover, probiotics modulate intestinal mucosal immune function, which plays a protective role in maintaining the intestinal barrier function[20].…”
Section: Discussionmentioning
confidence: 99%
“…Bifidobacterium is an anaerobic Gram-positive bacteria, with 32 subspecies, of which 28 subspecies have been detected in the human gut[13]. Intestinal bifidobacteria appear within 3 to 4 d postnatally, and bifidobacteria comprise approximately 25% of total intestinal bacteria[20].…”
Section: Discussionmentioning
confidence: 99%
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“…LPS induces the production of inflammatory cytokines, resulting in subsequent liver tissue injury (5). Furthermore, LPS induces Kupffer cell activation via the Toll-like receptor 4 signaling pathway, and subsequently activates nuclear factor (NF)-κB and initiates the release of inflammatory cytokines, including interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α (6,7).…”
Section: Introductionmentioning
confidence: 99%