2017
DOI: 10.12991/mpj.2017.27
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Biflavonoids from the leaves and stem bark of Garcinia griffithii and their biological activities

Abstract: The phytochemical and biological activity of the leaves and stem barks of Garcinia griffithii have been investigated. Extraction and chromatographic purification of the leaves and stem barks extracts have successfully afforded five biflavonoids namely amento-4''-methylether (1), 3,8''-binaringenin (2), morelloflavone (3), 3,8''-binaringenin-7''-O-glucoside (4) and morelloflavone-7''-Oglucoside (5), together with squalene (6), canophyllol (7), friedelin (8) and β-amyrin (9) which were characterized spectroscopi… Show more

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Cited by 10 publications
(12 citation statements)
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“…L-DOPA was used as the substrate and mushroom tyrosinase as the enzyme. [16][17] The assays were conducted in 96-well microtiter plate, and Epoch Biotek reader was used to measure the absorbance at 475 nm. Mushroom tyrosinase enzyme (MTE) was prepared from the stock solution to 480 units/ mL in PBS.…”
Section: Tyrosinase Inhibitory Activitymentioning
confidence: 99%
“…L-DOPA was used as the substrate and mushroom tyrosinase as the enzyme. [16][17] The assays were conducted in 96-well microtiter plate, and Epoch Biotek reader was used to measure the absorbance at 475 nm. Mushroom tyrosinase enzyme (MTE) was prepared from the stock solution to 480 units/ mL in PBS.…”
Section: Tyrosinase Inhibitory Activitymentioning
confidence: 99%
“…1) revealed the presence of twelve phenolic compounds, comprising five bioflavonoids, four flavones, two flavonols and one flavan-3-ol. The identification of the phenolic compounds was performed taking into account previous reports of chemical studies in Garcinia 6,25,26 and other plant species. 27 Bioflavonoids were the most abundant compounds present in G. brasiliensis.…”
Section: Identification Of Phenolic Compounds In the Ethyl Acetate Frmentioning
confidence: 99%
“…leaf extract. 26 Due to the consistent presence of these compounds in these species, they are considered to be chemotaxonomic markers for the genus Garcinia. Compound 10 ([M − H] − at m/z 703) was identified as binaringenin-7″-O-glucoside, taking into account the findings presented by Salleh et al, 26 who studied the leaves and stem bark extracts from G. griffithii.…”
Section: Identification Of Phenolic Compounds In the Ethyl Acetate Frmentioning
confidence: 99%
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