2021
DOI: 10.1016/j.ejmech.2021.113378
|View full text |Cite
|
Sign up to set email alerts
|

Biguanides: Species with versatile therapeutic applications

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

0
48
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
9

Relationship

1
8

Authors

Journals

citations
Cited by 46 publications
(48 citation statements)
references
References 460 publications
0
48
0
Order By: Relevance
“…There are four synthesis routes for preparation of proguanil derivatives [ 18 ], we choose the route with highest yield and experimental feasibility as shown in Scheme 1 . Ten new compounds were successfully obtained and named 2C – 10C and 12C .…”
Section: Discussionmentioning
confidence: 99%
“…There are four synthesis routes for preparation of proguanil derivatives [ 18 ], we choose the route with highest yield and experimental feasibility as shown in Scheme 1 . Ten new compounds were successfully obtained and named 2C – 10C and 12C .…”
Section: Discussionmentioning
confidence: 99%
“…More speculatively, antiviral properties have been attributed to molecules containing a biguanide moiety, including metformin ( Kathuria et al, 2021 ). Indeed, metformin was used in the management of influenza in 1950 (when it was known as “flumamine”), 7 years before its entry into clinical use for type 2 diabetes ( Bailey et al, 2007 ).…”
Section: Metformin and Covid-19mentioning
confidence: 99%
“…Biguanides are known to have a wide variety of therapeutic indications. Among others they are used as antidiabetic, antimalarial, anticancer, antimicrobial and antiviral agents [ 6 ]. From all biguanides, most research has been done with metformin.…”
Section: Metforminmentioning
confidence: 99%