Bilateral Ampiginous Choroiditis following Confirmed SARS-CoV-2 Infection

Carvalho, Erika Moreira; Teixeira, Fernando Henrique Flores; Paiva, Alexandre de Carvalho Mendes; Santos, Nathalia Silva; Biancardi, Ana Luiza; Curi, André Luiz Land

doi:10.1080/09273948.2022.2049317

Cited by 4 publications

(1 citation statement)

References 5 publications

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“…Previously, reported cases of posterior uveitis associated with post or concurrent COVID-19 infection have mainly involved retinal vasculitis, ranging from mild degrees to frosted branch angiitis [22][23][24][25][26]. Other ndings include retinal in ltrates, panuveitis, and white dot syndrome [27][28][29][30][31][32]. K OY et al reported a case of granulomatous panuveitis one week following COVID-19 infection in a 46-year-old female who exhibited similar posterior segment ndings to our patient.…”

Section: Discussionmentioning

confidence: 99%

Post-COVID-19 Retinal Manifestations in Pediatric Patient with Retinoblastoma: A Case Report

Ng,

Tungsattayathitthan,

Trinavarat

et al. 2023

Preprint

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Background The coronavirus disease 2019 (COVID-19) has been associated with various ocular manifestations, with limited literature on posterior segment findings in pediatric cases, especially in the context of retinoblastoma (RB). We present a unique case of a pediatric patient with unilateral RB who developed posterior uveitis and retinal vasculitis in the fellow eye following a COVID-19 infection. Case presentation A one-year and four-month-old boy with unilateral RB developed small retinal infiltrates and retinal vasculitis in the fellow eye at six months after a COVID-19 infection. Laboratory work-up did not identify infectious or specific autoimmune disorders. Given the critical nature of retinoblastoma, it raised concerns about a tumor-related cause in the fellow eye. Ancillary investigations, including fundus fluorescein angiography, were performed to differentiate RB-related changes. However, the results did not align with the typical features of RB. Spontaneous resolution of retinal lesions and retinal vasculitis was observed six weeks later. Conclusions Pediatric patients with posterior uveitis or retinal vasculitis post-COVID-19 should undergo comprehensive diagnostic workup, akin to adults, to exclude alternative causes before attributing it to SARS-CoV-2-induced immune responses. Notably, in unique cases like RB, a thorough evaluation of tumor-related cause is imperative.

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Section: Discussionmentioning

confidence: 99%

Post-COVID-19 Retinal Manifestations in Pediatric Patient with Retinoblastoma: A Case Report

Ng,

Tungsattayathitthan,

Trinavarat

et al. 2023

Preprint

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Bilateral Relentless Placoid Chorioretinitis Following Pfizer–BioNTech COVID-19 Vaccination: Specific Antigenic Trigger or Nonspecific Immune Activation?

Dutt

Lam

Richards

2023

Ocular Immunology and Inflammation

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Serpiginous Choroiditis After COVID-19 Infection

Seddigh,

Pinto,

Zaki

et al. 2024

Journal of VitreoRetinal Diseases

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Purpose: To present the first case of macular serpiginous choroiditis after COVID-19 infection. Methods: A single case was analyzed. Results: A 28-year-old previously healthy man presented with severe unilateral vision loss in the left eye. A fundus examination showed severe atrophic pigmentary changes that corresponded with optical coherence tomography (OCT) findings of a rapidly progressing amoeboid-like lesion disrupting the ellipsoid zone and retinal pigment epithelium. Multimodal imaging, including fundus autofluorescence, OCT angiography, and indocyanine green angiography, was supportive of serpiginous choroiditis. After a comprehensive systemic workup, the diagnosis of macular serpiginous choroiditis was confirmed. No improvement was seen with high-dose steroids; therefore, an immunosuppressive regimen was initiated. Conclusions: An exaggerated choroidal inflammatory response may be triggered by a COVID-19 infection, although causation cannot be inferred. Retinal manifestations should be considered when assessing patients presenting with visual symptoms after COVID-19 infection.

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Bilateral Ampiginous Choroiditis following Confirmed SARS-CoV-2 Infection

Cited by 4 publications

References 5 publications

Post-COVID-19 Retinal Manifestations in Pediatric Patient with Retinoblastoma: A Case Report

Post-COVID-19 Retinal Manifestations in Pediatric Patient with Retinoblastoma: A Case Report

Bilateral Relentless Placoid Chorioretinitis Following Pfizer–BioNTech COVID-19 Vaccination: Specific Antigenic Trigger or Nonspecific Immune Activation?

Serpiginous Choroiditis After COVID-19 Infection

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