Bilateral angiosarcoma of the breast

Khoshim, Mohammed H. B.; Sadiq, Saleem; Ajarim, Dahish; Jamjoom, Zain Alabedeen B.

doi:10.1007/bf02471057

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…Although rare, there are few case reports describing bilateral angiosarcoma of both breasts. [1,2] More than half of the cases are directly associated with irradiation of breast carcinoma and primary angiosarcoma is very rare. [3] In younger patients, the lesion was not associated with previous radiotherapy but older patients are usually presented after radiotherapy.…”

Section: Introductionmentioning

confidence: 99%

Bilateral angiosarcoma of breast in a young lady

Devleena

Maji

et al. 2011

Indian Journal of Medical and Paediatric Oncology

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We report a young lady with bilateral angiosarcoma of breast because of its rarity. A 29 year old unmarried female presented with bilateral breast lump. She underwent bilateral mastectomy with axillary dissection histopathology of which showed low grade angiosarcoma of left breast and high grade angiosarcoma of right breast. CT Thorax revealed right hilar and right mediastenal lymph nodes. She was treated with radiotherapy and chemotherapy postoperatively.

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Section: Introductionmentioning

confidence: 99%

Bilateral angiosarcoma of breast in a young lady

Devleena

Maji

et al. 2011

Indian Journal of Medical and Paediatric Oncology

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Angiosarcoma of the breast: Immunohistochemical demonstration of steroid receptors and literature review

et al. 1996

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A 44-year-old female with bilateral angiosarcoma of the breast with multiple skin metastases is reported. She presented with a 6x8 cm and 1x1 cm mass in her left and right breasts, respectively, and multiple skin lesions around the chest. Histologically, the excised tumor was diagnosed as angiosarcoma of the breast with skin metastasis. Tumor cells were immunohistochemically positive with factor VIII-related antigen, CD34, alpha-smooth muscle actin and vimentin, and positive with UEA-I lectin. The majority of tumor cell nuclei expressed progesterone receptor (PgR) protein but estrogen receptro (ER) protein and androgen receptor (AR) protein were nagative. According to the literature, angiosarcoma of the breast mostly affects females in their fourth (33%) and fifth (40%) decades (mean age, 39.5 +/- 10.7 years). The survival rate depends on tumor size and tumor differentiation. The 3-year survival rate is 86% in patients with a tumor size less than 5 cm, and 90% in well-differentiated group I lesions.

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