Bilateral angle-closure during hospitalization for coronavirus disease-19 (COVID-19): A case report

Barosco, Guido; Morbio, Roberta; Chemello, Francesca; Tosi, Roberto; Marchini, Giorgio

doi:10.1177/11206721211012197

Cited by 11 publications

(6 citation statements)

References 21 publications

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“…Sysytemic conditions affect two eyes but clinical presentations might be different in two eyes. 16 With the exception of favipiravir, no drug use was present among the patients.Since the patients did not have respiratory distress, no inhalation agent was given.…”

Section: Discussionmentioning

confidence: 93%

Acute angle-closure glaucoma concurrent with COVID 19 infection; case report

Özmen

Aksoy

Çakır

et al. 2022

European Journal of Ophthalmology

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Introduction To report three cases that developed acute angle-closure glaucoma on the background of hyponatremia due to COVID 19 infection. Methods Data of patients with positive PCR result for COVID 19 infection and concurrent findings of acute angle-closure glaucoma were analysed retrospectively. Results The common characteristic of all cases was positive PCR test for COVID 19 infection taken from the nasopharyngeal swab 4 or 5 days ago. Their serum sodium levels were lower than 135 mmol / L. At the initial ophthalmic examination, all cases had diffuse corneal edema with shallow anterior chambers and mid-dilated non-reacting pupils.The choroid was evaluated as normal by ocular ultrasonography. Intraocular pressures (IOP) of the first, second, and third cases were 35 mmHg, 44 mmHg, and 40 mm Hg, respectively. 5–10 cc/kg mannitol was given to all patients intravenously within 30 min. Simultaneously, they began to use oral acetazolamide, topical pilocarpine, beta-blocker, and prednisolone acetate drops.After stabilization of IOP, Neodymium-doped yttrium aluminum garnet;(ND: YAG) Laser iridotomy was performed on all patients. No additional fluid therapy was given to the patients other than mannitol, and it was determined that the blood sodium level remained at normal levels after diuresis. Discussion Hyponatremia is the most common electrolyte disorder in COVID 19 infection. Hyponatremia may cause an angle-closure attack in patients with shallow anterior chamber angles.Therefore, one should be aware of the possibility of angle-closure glaucoma in patients who develop hyponatremia due to COVID 19 disease. Suspected patients should be referred to the ophthalmology department.

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Section: Discussionmentioning

confidence: 93%

Acute angle-closure glaucoma concurrent with COVID 19 infection; case report

Özmen

Aksoy

Çakır

et al. 2022

European Journal of Ophthalmology

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“…These medications included antitussives, nasal decongestants, promethazine compound linctus, diphenhydramine compound linctus, identified syrup (comprising pseudoephedrine and triprolidine), chlorpheniramine, and a variety of antihistamines. [ 13 , 15 ] In our study, 38 eyes were administered antipyretic drugs, including ibuprofen and paracetamol, which may have played a role in triggering APAC. Additionally, recent literature indicates that COVID-19 vaccinations may precipitate APAC in certain individuals, although the underlying mechanisms remain elusive.…”

Section: Discussionmentioning

confidence: 99%

“…While previous case reports and studies have explored the occurrence of APAC attacks during the COVID-19 pandemic, most of them were based on a small number of cases or focused on the clinical characteristics of APAC during lockdown. [12][13][14][15] However, the potential risk factors and clinical characteristics of APAC patients during a COVID-19 outbreak without lockdown remain unexplored. Our investigation assumes that the systemic inflammation and vascular abnormalities associated with COVID-19 may contribute to the pathophysiology of APAC, either by exacerbating preexisting conditions or by initiating new pathogenic processes in the eye.…”

Section: The Authors Have No Conflicts Of Interest To Disclosementioning

confidence: 99%

Increased incidence of acute primary angle closure during the COVID-19 outbreak in China: A retrospective analysis

Liang,

Yang,

et al. 2024

Medicine

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This study aimed to investigate the incidence and clinical characteristics of acute primary angle closure (APAC) during the Coronavirus Disease 2019 (COVID-19) pandemic in China. This was a retrospective study of patients diagnosed with APAC in a glaucoma clinic over a 5-year period. We compared the number of APAC cases during the COVID-19 outbreak (December 7, 2022 to January 7, 2023) with those during the same period in previous years and 2 months prior to the outbreak. We also collected data on the demographic and clinical features of APAC patients, such as age, sex, disease course, visual acuity, intraocular pressure (IOP), and lens opacity. We included 95 eyes of 88 patients with APAC were included. Of these, 65 were female and 23 were male. The mean age was 68.0 ± 8.1 years. The median disease course was 10.8 ± 9.5 days. There was a significant increase in the number of APAC cases during the COVID-19 outbreak compared with the same months over a 5-year period (44 vs 51, P < .001). A higher proportion of women developed APAC during the outbreak period than during the non-outbreak period (P < .001). Eyes with APAC in the outbreak period had a lower mean IOP than those in the preceding 6 months (40.5 ± 8.8 mm Hg vs 46.1 ± 10.1 mm Hg; P = .043). No significant differences were observed in disease duration, lens opacity, or bilateral or unilateral onset between the 2 groups. Our study suggests a potential correlation between APAC and COVID-19, marked by a significant surge in APAC cases concurrent with the COVID-19 outbreak. However, the underlying mechanisms and preventive strategies remain to be elucidated.

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“…Due to risk factors like invasive mechanical ventilation, prone position, and multiresistant bacterial exposure, Intensive care unit (ICU) patients may develop IOP elevation [1]. In ICU patients, acute angleclosure glaucoma can be observed by the prone position and use of drugs such as anticholinergics and sympathomimetics [1] , [22,23]. In our study, only 2 patients were followed up in ICU.…”

Section: Pappazoglu Et Al Reported No Relevant Changes In Iop Values ...mentioning

confidence: 99%

The Course of Glaucoma in Recovered COVID-19 Patients

Sevimli

Saygın

2022

Preprint

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Purpose To observe the course of glaucoma progression after coronavirus disease 2019 (COVID-19) treatment of patients with a previous history of glaucoma. Design Multicentric observational case-control study Materials and Methods This observational case-control study included total 74 patients with COVID-19 infection who were diagnosed with glaucoma previously. The study focused on the left eye of 37 patients each were treated as inpatient or outpatient. Age, gender, existence of systemic and ocular diseases, symptoms, laboratory results, drugs used for COVID-19 and glaucoma, length of hospital stay, intraocular pressure (IOP), and central corneal thickness (CCT) values were recorded. Peripapillary retinal nerve fiber layer thickness (ppRNFLT), ganglion cell–inner plexiform layer complex thickness (GCIPLT) and vertical cup-disc (C-D) ratio results were compared before (pre-COVID-19) and after (post-COVID-19) COVID-19 treatment in both groups. Results A significant increase was observed in IOP values in both inpatient and outpatient groups (p = 0,02, p < 0,01 respectively) after COVID-19 infection. However, mean difference (MD) was higher in inpatient group for IOP levels (-1,76). Inpatient and outpatient groups showed statistically significant decrease in GCIPLT values post-COVID-19 (p < 0,01 and p = 0,02, respectively). In addition, MD value was higher in inpatient group (2,72). A significant decrease was observed in ppRNFLT values in inpatient group after COVID-19 infection (p = 0,03). In both groups, the mean C-D ratio was higher post-COVID-19. Conclusion PpRNFLT and GCIPLT values were reduced and IOP and C-D ratio values were increased in glaucoma patients after COVID-19 infection. Infection progression observed to be worse in inpatient group.

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Bilateral angle-closure during hospitalization for coronavirus disease-19 (COVID-19): A case report

Cited by 11 publications

References 21 publications

Acute angle-closure glaucoma concurrent with COVID 19 infection; case report

Acute angle-closure glaucoma concurrent with COVID 19 infection; case report

Increased incidence of acute primary angle closure during the COVID-19 outbreak in China: A retrospective analysis

The Course of Glaucoma in Recovered COVID-19 Patients

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