Bilateral ankyloblepharon filiforme adnatum associated with cardiac defects

Abstract

Ankyloblepharon filiforme adnatum (AFA) is a rare congenital anomaly and its presentation always indicates the possibility of other important anomalies. AFA is classified into four subgroups based on the associated abnormalities. Here we report a case of AFA associated with cardiac defects happened to an in vitro fertilization (IVF) female baby whose mother is elderly parturient (more than 43-year-old), and the baby was treated one day after birth.

Ankyloblepharon filiforme adnatum- a case report & review of literature

“…AFA may present as an isolated anomaly [6] such as in our patient or in association with the wide spectrum of congenital abnormalities including cleft palate and hare lip [7,8] hydrocephalus, meningomyelocele, and imperforate anus [9] bilateral syndactyly [10], patent ductus arteriosus [11], ventricular septal defect [12] and in association with various syndromes like Edwards′ syndrome 13 , Hay-Wells syndrome (a variant of the ectodactyly-ectodermal dysplasia-cleft lip palate syndrome) [14], the popliteal pterygium syndrome [15] etc. It usually presents in both the eyes but may be unilateral rarely [5,16].…”