Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue

Abstract

Renal cell carcinoma (RCC) has a propensity for distant organ metastasis and late recurrence, involving not only the ipsilateral but also contralateral kidney. Lingual metastasis by RCC is rare. We present an unusual case of bilateral asynchronous RCC. Involvement of the right kidney was discovered only after a metastatic tongue lesion was diagnosed. The original RCC had been treated by left nephrectomy 14 years previously. Due to end-stage primary pulmonary malignancy, and poor function of the remaining kidney, immunotherapy was unsuitable. Palliative local resection of the lingual metastasis alleviated functional difficulties and was preventative against airway obstruction, but the patient died five months later.

Renal cell carcinoma metastatic to the maxillary gingiva: A case report and review of the literature

“…The full listing of cases can be found in Table 1 . [ 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 ]…”

Lingual metastasis as an initial presentation of renal cell carcinoma: a case report

“… Interferon. Sunitinib and sorafenib later 24 (alive) Ghazali et al ., 2012 [ 13 ] 64/F History of nephrectomy for RCC 14 years previously. Lump on the tongue Contralateral kidney Excision 5 Tunio et al ., 2012 [ 14 ] 35/M History of nephrectomy for RCC.…”

“…The common clinical presentation includes a rapidly growing mass that often causes hemorrhage [ 23 ], as in our case. Other symptoms have been reported, such as dysphagia and dysarthria, which may reflect the mass effect [ 13 ].…”

A rare metastasis to the tongue and skin of the lower eyelid. A clinical case report and review of the literature

“…В большинстве описанных случаев (31 из 64) лечение метастазов в язык хирургическое. Наиболее часто выполнялось иссечения метастазов, реже -резекция языка (3 случая) [33][34][35], частичная глоссэктомия (в одном случае) [36], глоссэктомия/резекция с лимфодиссекцией (3 случая) [3,6,37], в одном случае описана эмболизация левой язычной артерии при кровотечении из метастаза в язык [38]. В нескольких случаях хирургическое лечение сочеталось с лучевой терапией (ЛТ) [3,7,26,39], в 2-х случаях применялась исключительно лучевая терапия [40,41].…”