Bilateral breast cancer associated with diffuse scleroderma

Pineda, Víctor; Salvador, Rafael; Soriano, José

doi:10.1016/s0960-9776(03)00007-9

Cited by 6 publications

(5 citation statements)

References 11 publications

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“…Retrospectively, our patient was probably experiencing early symptoms of CREST syndrome prior to her breast cancer diagnosis. Interestingly, there is evidence suggesting increased incidence of breast cancer in scleroderma patients (3).…”

Section: Discussionmentioning

confidence: 99%

Imaging Surveillance of the Breast in a Patient Diagnosed with Scleroderma after Breast-Conserving Surgery and Radiotherapy

et al. 2008

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Collagen vascular disease (CVD), particularly scleroderma, is a contraindication to radiation therapy because of increased risk of fibrosis. We report a patient with early stage breast cancer diagnosed with scleroderma after breast-conserving surgery and radiation. She developed marked breast fibrosis, rendering mammographic, sonographic, and clinical surveillance ineffective. She has subsequently been followed with magnetic resonance imaging (MRI) of the breast. We illustrate this case and review the literature relating to CVD and radiation therapy. MRI may be a suitable surveillance method in this situation.

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Section: Discussionmentioning

confidence: 99%

Imaging Surveillance of the Breast in a Patient Diagnosed with Scleroderma after Breast-Conserving Surgery and Radiotherapy

et al. 2008

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“…It was suggested that radiation induces neoantigens, which affect fibroblasts or endothelial proteins and ⁄ or alter the collagen elastic proteins (7). The association between breast cancer and scleroderma has been put forward and also the possible progression of localized scleroderma with radiation treatment (7,16,17). A report by Ullen et al described morphea following a treatment for asynchronous endometrial and breast cancer.…”

Section: Discussionmentioning

confidence: 99%

Morphea of the Breast: Case Reports and Review of Literature

Shetty¹,

Lewis

Thrush³

2007

Breast Journal

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Morphea of the breast is an uncommon skin condition associated with autoimmune disorders and has also been described following radiotherapy. The inflammatory stage of morphea can commonly be mistaken for a breast abscess or inflammation. We report two cases of localized scleroderma affecting the breast with no history of autoimmune disease or radiation treatment. In both the cases, the lesions improved with the use of topical steroids.

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“…An overexpression of connective tissue growth factor and collagen type I has been observed in patients with lung cancer [56]. Sclerodermalike skin lesions have been reported in patients with cancer of the stomach, breast, lungs, nasopharynx, together with with melanoma and sarcoma [1,7,8,[57][58][59][60][61][62][63].…”

Section: Review Articlesmentioning

confidence: 99%

Coexistence of systemic sclerosis, scleroderma-like syndromes and neoplastic diseases

Ciołkiewicz

Domysławska²,

Ciołkiewicz³

et al. 2012

Polish Archives of Internal Medicine

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Coexistence of systemic sclerosis, scleroderma-like syndromes and neoplastic diseases 119 REVIEW ARTICLES Neoplastic diseases and rheumatic syndromes A number of rheumatic diseases coexisting with neoplasm of various origins have been reported. Neoplastic lesions changes may evoke the paraneoplastic rheumatic syndromes. Moreover, they may be a complication of chronic rheumatic disease [1]. Paraneoplastic syndrome is defined as a sign or a constellation of signs and symptoms which are secondary to the presence of a malignancy. These symptoms may be induced to the substances secreted by the neoplasm (hormones and other biologically active substances) or to the immune system response to tumor cells (autoimmunological reactions, immune complexes, immune system suppression) and may involve many organs and systems. Paraneoplastic syndromes are not related to

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Bilateral breast cancer associated with diffuse scleroderma

Cited by 6 publications

References 11 publications

Imaging Surveillance of the Breast in a Patient Diagnosed with Scleroderma after Breast-Conserving Surgery and Radiotherapy

Imaging Surveillance of the Breast in a Patient Diagnosed with Scleroderma after Breast-Conserving Surgery and Radiotherapy

Morphea of the Breast: Case Reports and Review of Literature

Coexistence of systemic sclerosis, scleroderma-like syndromes and neoplastic diseases

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