2017
DOI: 10.1093/ejcts/ezx350
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Bilateral cavitary multidrug- or extensively drug-resistant tuberculosis: role of surgery†

Abstract: Thoracic surgery may significantly improve patients' outcomes and even result in a cure in a good portion of patients with bilateral cavitary MDR and XDR TB and should be considered as the essential element of multimodality treatment for MDR and XDR TB, even in patients with bilateral cavitary disease and borderline respiratory reserves.

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Cited by 14 publications
(11 citation statements)
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References 22 publications
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“…Multi-stage operations give a chance for recovering, while bilateral resections give hope to those who otherwise have no choice. While the published data on bilateral resections are encouraging (107), the devil, as usual, is in the details. One's lifelong experience and the old fox's seventh sense in patient selection are hard to explain in numbers like odd ratios and P values.…”
Section: Surgical Detailsmentioning
confidence: 97%
See 3 more Smart Citations
“…Multi-stage operations give a chance for recovering, while bilateral resections give hope to those who otherwise have no choice. While the published data on bilateral resections are encouraging (107), the devil, as usual, is in the details. One's lifelong experience and the old fox's seventh sense in patient selection are hard to explain in numbers like odd ratios and P values.…”
Section: Surgical Detailsmentioning
confidence: 97%
“…The place of resective surgery is open for discussion as there are many divergent opinions. Language barriers accepted, it is obvious that there is a distinct way, led by the robust Russian (and ex-Soviet Union states) experience (106,107), of favouring resection, while the majority of publications from the Far East show a more restrained attitude (100,(108)(109)(110). There is an understandably highly conservative attitude in the high income low incidence countries, a stance recently challenged by mass migration and global tourism.…”
Section: Indicationsmentioning
confidence: 99%
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“…In summary, all major guidelines are consistent in recommending surgery in selected cases, following chemotherapy and favouring elective partial lung resection when possible, based on specific indications: failure of drug therapy, relapse, localized (e.g., cavity) or extensive pulmonary TB, clinical complications (e.g., haemoptysis or empyema) [39]. However, recent evidence suggests that bilateral surgery can also be safe and effective [40].…”
Section: Evaluating the Role Of Surgery Through Ipdmentioning
confidence: 99%