Bilateral choanal atresia and paranasal sinus hypoplasia in an adult patient with hypogammaglobulinaemia

Abstract

We present an unusual case of a young female patient presenting with bilateral choanal atresia, which was probably acquired, associated with nasal and paranasal sinus hypoplasia and hypogammaglobulinaemia.

Chronic bullous disease of childhood and pneumonia in a neonate with VATERL association and hypoplastic paranasal sinuses

“…Hypoplastic paranasal sinuses and bilateral choanal atresia associated with hypogammaglobulinemia are reported in an adult with a history of repeated chest infections and pneumonia. 4 An evaluation for immunodeficiency in our patient was not completed before she died.…”

Congenital Bilateral Adult Choanal Atresia Undiagnosed until the Second Decade: How We did it

“…Of the eight documented cases of bilateral choanal atresia 1,3–8,14 , in the literature, only one patient had restenosis, which required revision surgery. 4 …”

Bilateral choanal atresia in an adult - management with mitomycin C and without stents: a case report

“…The typical clinical picture is cyclic cyanosis and dyspnea that worsens during feeding and improves during crying. There are only three cases of bilateral choanal atresia in adults reported in the literatures [3,5,6]. …”

“…El-Sawy et al[5] reported a 24-year-old patient with bilateral nasal obstruction and total loss of sense of smell and hypogammaglobulinemia. Computer tomography of this patient revealed aplasia of frontal and sphenoid sinuses and hypoplasia of the inferior and middle turbinates.…”

“…The atresia may be complete or incomplete[4]. Bilateral choanal atresia is very rare in adults [3,5,6]. Newborns are obligatory nasal breathers, therefore bilateral choanal atresia is often diagnosed at birth and treated with early surgery.…”